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. 2018 Mar 1;141(3):e20174067. doi: 10.1542/peds.2017-4067

Kaur R, Morris M, Pichichero ME. Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era. Pediatrics. 2017;140(3):e20170101

PMCID: PMC8190965  PMID: 29490905

An error occurred in the article by Kaur et al, titled “Epidemiology of Acute Otitis Media in the Postpneumococcal Conjugate Vaccine Era” published in the September 2017 issue of Pediatrics (2017;140(3): e20170181; doi:10.1542/peds.2017-0181). In the authors’ database, the BREASTFEEDING variable was represented as an ordinal variable, assuming values in the set {0,50 100}. The intention was to represent BREASTFEEDING as a dichotomous factor in a logistic regression model (combining 50 and 100 into a single factor level), in which case the odds ratio can be correctly estimated by exp(b), where b is the coefficient associated with BREASTFEEDING. However, BREASTFEEDING was mistakenly left as a numerical variable with range [0100]. The main effect on the fitted model was to approximately rescale the BREASTFEEDING coefficient, and its SE, by a factor of close to 1/100 (the mapping is not exact, due to the conversion of three distinct values {0,50 100} to two values {0,1}). The authors recalculated the model, using the originally intended dichotomous factor representation of BREASTFEEDING. BREASTFEEDING remains significant, and the odds ratio is now correctly reported, with a change in the order of magnitude compatible with the rescaling effect just described. In addition, the remaining covariate effects are changed only minimally. A corrected Table 8 appears below.

TABLE 8.

Multivariable Analysis of Factors Associated With sOP Condition

Variable Regression Coefficient Odds Ratio 95% CI P
Constant −3.17
Male sex 0.99 2.69 1.90–3.82 0.005
Breastfed −0.92 0.40 0.28–0.57 0.011
Family history of AOM 0.80 2.23 1.62–3.06 0.013
Daycare attendance 1.19 3.29 2.39–4.53 0.0002

—, reference.


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