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. 2021 Jun 25;16(6):e0253734. doi: 10.1371/journal.pone.0253734

Individual- and group-level network-building interventions to address social isolation and loneliness: A scoping review with implications for COVID19

Reza Yousefi Nooraie 1,*,#, Keith Warren 2,#, Lisa A Juckett 3,#, Qiuchang A Cao 2,#, Alicia C Bunger 2,#, Michele A Patak-Pietrafesa 2,#
Editor: Noleen McCorry4
PMCID: PMC8232435  PMID: 34170980

Abstract

Purpose

Worldwide mandates for social distancing and home-quarantine have contributed to loneliness and social isolation. We conducted a systematic scoping review to identify network-building interventions that address loneliness and isolation, describe their components and impact on network structure, and consider their application in the wake of COVID19.

Methods

We performed forward and backward citation tracking of three seminal publications on network interventions and Bibliographic search of Web of Science and SCOPUS. We developed data charting tables and extracted and synthesized the characteristics of included studies, using an iteratively updating form.

Findings

From 3390 retrieved titles and abstracts, we included 8 studies. These interventions focused on building networks at either individual- or group-levels. Key elements that were incorporated in the interventions at varying degrees included (a) creating opportunities to build networks; (b) improving social skills; (c) assessing network diagnostics (i.e. using network data or information to inform network strategies); (d) promoting engagement with influential actors; and (e) a process for goal-setting and feedback. The effect of interventions on network structures, or the moderating effect of structure on the intervention effectiveness was rarely assessed.

Conclusions

As many natural face-to-face opportunities for social connection are limited due to COVID19, groups already at risk for social isolation and loneliness are disproportionately impacted. Network-building interventions include multiple components that address both the structure of individuals’ networks, and their skills and motivation for activating them. These intervention elements could be adapted for delivery via online platforms, and implemented by trained facilitators or novice volunteers, although more rigorous testing is needed.

Introduction

The new norm of social/physical distancing and home quarantine after the COVID19 pandemic is contributing to the increase of social isolation and loneliness [1], which may have a significant impact on the physical and mental health of vulnerable populations [2]. Recent lockdowns due to COVID19 have brought the problems of social isolation and loneliness to the forefront of public attention [3], but these problems are not new, as loneliness is as old as human history. There is evidence that both social isolation and loneliness have increased in the United States in recent years [47].

Loneliness and social isolation are complex, multilevel phenomena. Social isolation refers to the lack of social contacts and engagement [8], whereas loneliness reflects subjective dissatisfaction with the quality or quantity of social contacts [9]. They are independently associated with physical illness, mental illness, and mortality [10]. Everyone can experience varying intensity and duration of loneliness and/or isolation at a certain point in life [11]. However, some populations such as those who are older, people who are LGBT or who have cognitive disabilities, are disproportionately affected by social isolation and loneliness, while gender, health and income also play a role [1214].

Loneliness/Isolation intervention as network-building interventions

Interventions to address isolation/loneliness generally aim to improve the quantity and quality of social relations with existing or new support individuals and groups. Network-building interventions are deliberate efforts to change social networks of individuals [15]. Social network analysis (SNA) is an important approach to assess how interventions addressing loneliness/isolation change social networks. SNA is a well-established approach that focuses on the relational patterns between network actors [16, 17] rather than considering them as separate units. In other words, SNA captures the interdependencies among network actors, whereas conventional research methodologies assume independence among network participants [18].

A popular approach to study the network outcomes of loneliness/isolation interventions is assessing the change in the size of personal networks [19], or individuals’ evaluation of support networks [20, 21]. Many existing social network tools, including Berkman Syme Social Network Index [22] and Lubben Social Network Scale [23], ask about the number of individuals in each important social role (family, friends, colleagues, etc.), and usually provide a single score. Some researchers ask about the number of important individuals in respondents’ social networks [24], create numerical scores based on a mix of the number and quality of social relations [25], or ask respondent’s evaluation of the number of people who can help each other in the community [26].

In the following section, we argue that the number of ties does not fully capture the relational complexity of social networks in which one is embedded.

Network structure and well-being

Several aspects of network structure influence individuals’ perception of loneliness and support. Here we provided a few examples:

Centrality represents the prominence of an actor in the network. The simplest measure of centrality, degree centrality, is the number of network connections an individual has (e.g. the number of friends, or family members) [27]. Degree centrality is one of the most commonly measured indicators of network structure, although authors do not necessarily refer to a count of connections as a measure of centrality [19]. In the case of social support, degree centrality could either be indegree (the number of people who offer you social support or who name you as a friend) or outdegree (the number of people to whom you offer social support or whom you name as a friend). Indegree centrality is positively correlated with emotional support [28]. However, a variety of other measures of centrality are associated with well-being. For example, betweenness centrality, the extent to which an individual is on paths between other members of the network, and closeness centrality, the extent to which short paths connect the individual and other members of the network, are positively correlated with measures of wellness [29]. Indirect connections also matter. Being connected to more people indirectly (through others) decreases the likelihood of depression [30].

The density (connectedness) of networks affects well-being. Compared to degree centrality which is about the number of relations from or towards ego (respondent), density is about the overall connectedness of personal network, which should include relationships among network members not including ego. Density of personal networks was shown to predict loneliness in college students, particularly in men [31, 32]. However, some studies failed to show the association between density and subjective loneliness [33, 34], or proposed that the effect of density of personal networks on life satisfaction is moderated by an individual’s personality (as individuals may differ in terms of satisfaction by embedding in denser networks) [35].

Reciprocity (bi-directionality) of social relations matters for several reasons. Qualitative studies have found that older individuals have an easier time accepting social support when it is offered as part of a reciprocal relationship, that is, when they feel that they have given (in the case of their children) or are giving help to the person who is helping them [36, 37]. Individuals who perceive reciprocity in their relationship with their best friends feel less lonely [38]. There is experimental evidence that reciprocity is a key factor in building trust in networks [39]. Reciprocal imbalance in relationships (over-benefiting and under-benefiting) may lead to mental distress and less satisfaction with relations [40]. All of these findings suggest that reciprocity may be one key to maintaining relationships once they are established.

Network clustering, or the degree to which groups of three individuals connect completely with each other, is another important feature. In a longitudinal analysis of a large population-based study, Cacioppo and colleagues (2009) found that loneliness occurs in clusters, particularly clusters of individuals that are peripheral to the social network [41]. People in more clustered networks tend to be healthier [29]. Experiments find that the search for cooperative partners produces clustering, suggesting that clustered networks play a role in maintaining cooperation in groups [42, 43]. Of course, the influence that clustered networks have on their members has a downside. DiFonzo et al (2014) find that clustering increases the social influence of the group but also increases the tendency of groups to strongly differentiate themselves from others [44].

Based on the abovementioned evidence, we argue that interventions addressing loneliness/social isolation may affect the structure of social networks beyond merely increasing the number and frequency of social relations to ego. They may change the reciprocity of relations, may affect formation of denser clusters, or may even selectively affect some regions of one’s social network (e.g. only improving the quality of intimate relations, or leading to bridging ties to new clusters). Given the need for more in depth analysis of the structural targets of interventions for loneliness/isolation, we conducted a systematic scoping review of studies assessing the effect of interventions to address loneliness and social isolation on the structure of social networks. We aimed to map the types and components of these interventions and methods/metrics of assessing structural changes in social networks. We evaluated how these interventions can be adapted to promote connectedness in the context of societies after COVID19.

Methods

We followed PRISMA-ScR guidelines for scoping reviews in the conduct of the literature review, data extraction/charting, and synthesis [45].

Literature search

Our search strategy involved forward/backward citation tracking of three seminal network intervention publications, Valente (2012) [15], Valente et al. (2015) [46], and Latkin & Knowlton (2015) [47], complemented by a bibliographic search in Web of Science and SCOPUS, performed in October 2019 (search strategy in S1 Appendix). To capture articles about relevant interventions for social isolation and loneliness that might not have been described using network intervention keywords, we also conducted a hand search of seminal reviews on the topic [1921, 48]. Articles identified through this search strategy were imported into the web-based review program, Covidence [49], before undergoing title/abstract review.

Study selection

To establish consistency in the study selection and data charting process, all authors completed a trial screening process in pairs (three sets of pairs total). Authors met biweekly from March 2020 –July 2020 to discuss points of disagreement and achieve consensus pertaining to title/abstract and full-text study inclusion. We included studies that intentionally aimed to change aspects of social networks to address isolation/loneliness, measured the network structure as study outcomes and/or used them to inform interventional strategies, and were available in English. We excluded studies that only reported the number of individuals one is connected to (network size) or only provided aggregate measures of quality and quantity of relations (such as Berkman Syme Social Network Index and Lubben Social Network Scale).

Data extraction and synthesis

A data-charting form was jointly developed by the reviewers to determine variables to extract. Pairs of reviewers independently extracted a calibration set of studies. Once the team demonstrated consensus and consistency in data charting on the calibration set, the information in each included study was extracted by one author. The group regularly met to discuss and resolve uncertainties and potential disagreements, and continuously updated the data-charting form. Categories included on the data charting form were as follows: author/year, sample, study setting, design, characteristics of network actors, the nature of network relations, characteristics of the intervention(s), theoretical underpinnings of the intervention(s) according to the authors, measures of network change and other outcomes, effectiveness of the intervention according to the authors, and implications. Result syntheses consisted of three steps: 1) descriptive summary describing details about study design, 2) thematic analysis for the categorization of network interventions, and 3) consideration for how these interventions could be adapted to contexts with limited physical and in-person contact opportunities, as manifested by COVID19 restrictions. We did not conduct quality appraisals of included studies, which is consistent with PRISMA-ScR guidelines given the exploratory nature of scoping review methodology and the heterogeneity of studies included in scoping reviews.

Results

Literature search and selection process

Of our initial 3390 references, we assessed the full texts of 233 articles, of which 17 studies were about the effect of interventions on social networks to address loneliness and isolation, of which 9 studies were excluded, as they either only reported the number of individuals one is connected to or developed single aggregate measures for quality and quantity of relations without providing information about the composition of social network and/or detailed information about relations to particular social groups/roles. We included eight studies that measured network structure before and after the intervention and/or incorporated network analysis as a component of the intervention (Fig 1). Three studies assessed interventions focusing on individual-level network building, and four studies assessed group-level network building interventions. Kasari et al. (2016) compared an individual-level with a group-level intervention, and consequently was included in both sections [50].

Fig 1. PRISMA flow diagram of the study selection.

Fig 1

Individual-level network interventions

The interventions in this category generally aimed to help the individuals with limited social connections (e.g. older adults and children and adults with intellectual, mental, and physical disabilities) strengthen/activate existing social relations or engage in activities to facilitate new relations or strengthen current ties (Table 1).

Table 1. Study characteristics, elements of network-building interventions, and main outcome measures.

Study Study design & Sample Characteristics Setting Network Ties Network-building intervention Network Analysis procedures & Measures Intervention Effectiveness
Individual-level interventions
Band et al. (2019) [51] Design: Pragmatic RCT with a wait-list control
Sample: Adults (18+) who are isolated or at risk of loneliness; n = 394
Study: Community organizations in two areas in the UK. Ties with family members, friends, acquaintances, healthcare professionals, local groups and pets Intervention level: Mixed: Network assessment was conducted online, in-person, or via phone. Individuals were connected to online resources.
Intervention summary: Generating Engagement in Network Involvement (GENIE): Online social networking tool to create opportunities for social involvement through social network mapping, tailoring of preferences and linking users to valued resources and activities, delivered by trained facilitators. Facilitators helped participants develop personal support maps using concentric circles representing tie strength, and various social roles including individuals, groups, and pets [no mention of alter-to-alter relations]
Measures: SF-12 Mental Health and Physical Health Composite scores
Loneliness, social isolation, well-being, Quality-adjusted life years, cost, Capability well-being, Collective efficacy in Network scale, engagement in new activities
Analysis: Social network composition change (only in intervention arm) [since no alter-to-alter relations are collected, the composition will likely only refer to ego’s relations]
Study in-progress (study protocol published)
Locke, et al. (2019) [53] Design: Case report, feasibility pilot
Sample: Elementary school students (grade 1–5) with Autism Spectrum Disorders; n = 4
2 public elementary schools in an urban district (85% of students are racial minorities & 70% of students receive free/reduced price lunch) Observed playground social interactions & in-class friendship ties Intervention level: In-person
Intervention summary: Remaking Recess is an adult-facilitated intervention to support social engagement of children with ASD when at recess. The intervention includes observing if children need additional support to engage with their peers, follow children’s lead, strengths and interests, providing direct instruction on social skills and games and activities to scaffold engagement, creating opportunities for reciprocal interactions, sustain engagement within an activity, coaching through difficult peer situations, work with typically developing peers to engage children with ASD, and eventually fading out supports to promote independence.
Measures: Sociometric survey of friendship networks within each class about students’ social network and their perception of “who hang out together”.
Analysis: Centrality of students (number of times the student identified by others as belonging to a group) was used to calculate social network inclusion score (individual’s centrality at each time divided by highest baseline centrality in class).
Decrease in solitary playground time;
Increase in joint engagement with peers.
Social network inclusion scores initially increased but declined at 6 week follow-up.
Osilla et al. (2016) [52] Design: Qualitative feasibility and acceptability assessment
Sample: Formerly homeless adults people with histories of AOD and HIV risk behaviors; n = 11 (8 men: 7 African American, 1 Latino/Hispanic; 3 Women: 2 African American, 1 Latina/Hispanic)
Organization that provides permanent supportive housing in Los Angeles County Social interactions Intervention level: In-person (computer assisted)
Intervention summary: Computer-assisted Motivational Network Intervention: Across 4 sessions (2-week intervals), participants complete a survey on drinking and unprotected sex and a name generator network survey followed by motivational discussions on the network map, the pros and cons of the patterns in the map, opportunities to discuss positive behavior change and goal setting for the following week.
Measures: No structural measures of personal networks reported
Analysis: Qualitative study
Residents reported that the intervention was helpful in discussing their social network, that seeing the network maps was more impactful than just talking about their network, and that the intervention prompted thoughts about changing their AOD use and HIV risk networks.
Kasari et al. (2016) [50] Design: RCT, comparing
SKILLS (group social skill training) and ENGAGE (peer-matched social activities)
Sample: Children (ages 6–11 in grades 1–5) with Autism Spectrum Disorder (IQ >65); n = 148; More than 50% were racial/ethnic minorities
Elementary schools Friendship ties Intervention level: In-person groups in schools
Intervention summary: SKILLS: 16 sessions of group participation in interactive classes on social skills training: Being a Social Detective; Greetings and Goodbyes; Body Talk (Nonverbals); Humor; Conversation; Dealing with Teasing; Perspective Taking; Dealing with Emotions; and Friendship Tips.
ENGAGE: Children with ASD and their typically developing peers (nominated through friendship survey or teacher nomination) engage in 16 sessions of group play activities, collectively establishing a daily schedule in order to encourage cohesiveness, conversational exercises, structured games, free play, improvised storytelling, and music. Peers were encouraged to take leadership of their own groups with supervision from adults as needed.
Measures: Sociometric survey of friendship networks within each class about students’ social network and their perception of “who hang out together”.
Analysis: Centrality of students at class (number of times the student identified by others as belonging to a group) was used to calculate social network Salience score (individual’s centrality at each time divided by highest baseline centrality in class).
All children significantly increased percent of time spent engaged with peers from pre- to post-treatment.
Those in the SKILLS group improved significantly more than those in the ENGAGE group (significant treatment effect).
Effect of treatment did not vary by site.
No significant change in network salience scores over time however, there were modest overall improvements in both groups.
Group-level interventions
van Asselt-Goverts, et al. (2018) [55] Design: Case report, qualitative assessment
Sample: Adults with mild to borderline intellectual disabilities and their support workers; n = 5
Organization providing support for people with intellectual disabilities in Netherlands Ties to family, friends, neighbors, colleagues, acquaintances & professionals Intervention level: In-person
Intervention summary: A 7-session semi-structured group training to strengthen or expand the networks of participants. Sessions were facilitated by experienced trainers and focused on talents and interests, network, neighborhood, wishes and dreams, plans for a supporters meeting, and evaluation. Exercises included role playing and making a personal map. Facilitators helped participants develop personal support maps using concentric circles representing tie strength, and various social roles including family, friends, neighbors, colleagues, other acquaintances, and professionals [no mention of alter-to-alter relations]. For each network member, the participants scored the frequency of contact, affection, types of support, and preferences. Participants re-evaluated their maps after the intervention.
Measures: No structural measures of networks were reported.
Analysis: Info gathered about each individual’s network size and the frequency and quality of relationships. Data were analyzed to look for increases in size, frequency, and quality of relationships.
The network results were presented for individual participants and varied by individuals.
In qualitative analysis, participants reported decreased loneliness and increased awareness, competence, autonomy and participation.
Gesell et al. (2013) [58] Design: Uncontrolled pre-post test
Sample: Parents of children at risk for obesity; n = 11
Community recreation center in Nashville, TN Advice and discussion ties with group members outside of training sessions Intervention level: In-person group meetings
Intervention summary: GROW intervention:
The network-building intervention involved 12-week group skill building sessions in which social network diagnostics were used to create an action plan and recommendations for each group and its leader and a menu of action steps. Group sessions functioned to establish a strong group identity through developing and working toward a shared common goal and group identity. Group social networks were restructured through strategic pairing of isolates with highly connected group members, calling isolates in groups and promoting their participation, pairing non-reciprocated links, bringing triads together, and pairing members from different subgroups in small group activities; re-assigning members to prevent formation of silos.
Measures: Network diagnostic tool involved identification of isolates and components/subgroups, and calculation of degree, density, reciprocity, transitivity, centralization, and average of inverse distance.
Analysis: descriptive presentation of network measures at week 4 and 12. Density was compared using boot-strapped t-test.
Perceived cohesion increased (non-significant);
Number of advice and discussion partners increased over time (non-significant);
Advice network density increased significantly;
Number of isolates remained stable;
Subgroups decreased (integrated into network);
Centralization increased in the advice network and decreased in the discussion network.
Gesell et al. (2016) [57] Design: Uncontrolled pre- post-test
Sample: Parents of children (3–6 years old) at risk for obesity; n = 305
Community recreation center in Nashville, TN Advice and discussion ties with group members outside of training sessions Intervention: In-person group meetings
Intervention summary: GROW intervention; explained above
Measures:network size (number of nominations) in advice and discussion networks
Analysis: comparison of the average number of nominations at week 3 and 6
Significant increase (from week 3 to 6) in cohesion and advice nominations;
Non-significant increase in discussion nominations;
New network nominations were associated with perceptions of group cohesion.
Tesdahl et al. (2015) [56] Design: Uncontrolled pre-post test
Sample: Expectant Latina and African American mothers; n = 59
Community recreation center in Nashville, TN People within the program with whom the respondent spoke about pregnancy-related health issues Intervention level: In-person, small groups
Intervention summary: The intervention included small-group activities aimed at achieving a common goal (e.g., planning an event for family and friends) with rotating leadership roles to increase group cohesion. The intervention also included social skills practice for building and strengthening positive support among family and friends, including identifying existing supports for prenatal health as well as gaps in support networks, identifying the benefits and attributes of supportive relationships, and learning how to build new and tend to supportive relationships.
Measures: Participants responded to name generator surveys at weeks 6 and 12 (later mixed together to create a cross-sectional network) to identify other study participants with whom they have spoken about well-being.
Analysis: The merged cross-sectional network (of weeks 6 and 12) was analyzed using Exponential Random Graph Modeling with tie existence between pairs of participants as the dependent variable, and total number of sessions the pair attended as the independent variable indicating program effect.
Participants created 3.5 ties on average;
Only 4% of ties at week 6 remained the same at week 12;
Similarity in physical activity level and due dates increased the likelihood of tie formation;
Attendance significantly impacted the formation of network ties among pairs of participants.

Study designs

Two studies were small case reports, small uncontrolled studies, or qualitative studies. Kasari et al. (2016) conducted an RCT comparing the individual-level intervention (matching subjects with typically developing peers in social activities and games) and a group-based social skills training (explained in the next section) [50]. Band et al. (2019) published the protocol for an upcoming pragmatic RCT of an online platform to develop personal maps, and connect adults to local and online activities and resources, compared to a wait-list control [51].

Intervention components

Interventions usually included elements of motivational training, reflection, and goal setting.

The interventions in two studies included assisting the participants to develop personal network maps, and reflect on their structure. In Band et al. (2019) [51] and Osilla et al. (2016) [52], facilitators would help participants develop their personal maps, through an online platform in Band et al. (2019) [51], and a computer-assisted face-to-face discussion in Osilla et al. (2016) [52]. The online interface in Band et al. (2019) [51] provided concentric circles representing tie strength, and various social roles including individuals, groups, and pets. In Osilla et al. (2016) [52], the process included a structured network interview, followed by discussions on visualizations. In Osilla et al. (2016) [52], the participants also identified relationships between network members, also known as “alters” (whether alter 1 knows alter 2), but in Band et al. (2019) [51], the questions were all about the relationships with ego (the focal actor), with no mention of alter-to-alter relations.

In three studies, the intervention included facilitation of social contact and exposure, either through connection to local activities as a general opportunity for network building [50, 51, 53], or engaging in social activities with natural peers (or friends with no disabilities) [50]. In one study the intervention also included social skills training [53]. Two studies also included patients’ family or support staff in the intervention [52, 53]. All studies described interventions consisting of several sessions lasting multiple weeks, to provide enough time for participants to reflect on their networks and make changes over time.

Two studies examined social network interventions that were administered in-person. In Band et al. (2019) [51] the intervention is an online platform to develop personal maps, and connect adults to local and online activities and resources. Similarly, Osilla et al. (2016) [52] assessed the effect of a computer-assisted motivational network intervention, in which the process of data collection and presentation of network maps was done on a tablet.

Outcomes

Two studies used sociometric network surveys to develop network structures and how they changed over time [50, 53]. Both studies calculated network salience/inclusion scores at each time point, using a method developed by Cairns & Cairns (1994) [54]. The score for each individual is the ratio of the number of times they were identified by others belonging to a group to the largest baseline score in class at baseline. Both studies showed that the intervention resulted in increased socialization of the participants (measured by the time spent with others). However, the change in network inclusion scores were modest and transient.

In their qualitative analysis, Osilla et al. (2016) [52] showed that visualization through the development of personal network maps was useful in helping participants build insight on the composition of their networks.

Group-level network interventions

Interventions in this category were administered in small groups and, in addition to network-building at individual levels, also aimed to facilitate communication, support, and role-modeling among peers within the groups (Table 1).

Study designs

Four studies were case reports and uncontrolled pre-post designs. Kasari et al. (2016) [50] conducted an RCT to compare an individual- and a group-level intervention.

Intervention components

Group-level interventions involved delivering social skills training [50, 55, 56], or providing opportunities for co-participation in activities of common interest [56]. Two studies involved peer support and training through pairing isolates with highly connected actors [57, 58], while another study encouraged peer support and training through co-participation of individuals and their support workers [55].

Three studies explicitly incorporated the analysis of network structure into their interventions. In van Asselt-Goverts et al. (2018) [55], development of and reflection on personal network maps was a component of group training. Facilitators helped participants develop personal support maps using concentric circles representing tie strength, various social roles (e.g. family, friends, neighbors), and frequency, type, and preference of relations to each alter. However, no alter-to-alter relation data were collected. In two studies [57, 58], the focus and content of group activities were guided by network diagnostics that involved the structural analysis of social networks (such as identification of isolates and components/subgroups, and calculation of degree, density, reciprocity, transitivity, centralization, and average of inverse distance). The network diagnostics informed strategies to modify structural characteristics.

Outcomes

van Asselt-Goverts et al. (2018) [55] reported the size, frequency, and functional characteristics of social relations to important social roles (family, friends, colleagues, neighbors, others). They also reported various qualitative themes explaining improvement in social connectivity of participants, including awareness, competence, autonomy and participation. Gesell et al. (2013) [58] reported the change in structural measures (e.g. density, reciprocity, clustering, isolates, etc.) over time. They reported a significant increase in the advice network density, an increase in network centralization and in network cohesion, over time. Gesell et al. (2016) [57] was developed based on the experience of pilot assessment in Gesell et al. (2013) [58], and reported significant improvement in the number of nominations in the advice network and subjective measure of cohesion. Kasari et al. (2016) [50] reported social network salience scores (see above). Tesdahl (2015) [56] developed an exponential random graph model to assess how personal, interpersonal, and structural features of the network were associated with the existence of ties between pairs of actors. The model showed that the total number of sessions that pairs of participants attended, as well as similarity in physical activity and pregnancy due date would significantly increase the chance that they are connected in the conversation network. However, they did not directly assess the effect of the intervention, since there were no parallel control groups or longitudinal assessments of network formation.

Discussion

Our review identified multiple interventions that may mitigate social isolation and loneliness among vulnerable individuals and groups. We describe these programmatic elements, their implications for network interventions generally, and potential applications to address social isolation and loneliness that has been exacerbated by COVID 19 pandemic.

Networks as intervention components

In this review, we identified key elements from both individual-level and group-level network-building interventions that address social isolation and loneliness in a framework shown in Fig 2. These elements, described below, consist of the following: (a) creating opportunities to build networks; (b) building social skills; (c) assessing network diagnostics; and (d) promoting network engagement.

Fig 2. Components of individual- and group-level network-building interventions; opportunities and barriers for post-COVID19 adaptation.

Fig 2

Creating opportunities for networking

Both groups of studies (e.g., individual-level and group-level) included interventions that provided opportunities for socialization and networking via participation in events and activities of common interest [50, 51, 53]. When opportunities exist, either in-person or online, this strategy facilitates natural network-building and expansion of the boundaries of social networks to a larger population of individuals with common interests. However, it seems that the mere provision of opportunities was ineffective in forming sustained social ties, and other active strategies are needed.

Building social skills

Building social skills through lectures, role modeling, and games were used in some individual- and group-level studies [50, 52, 53, 5557]. This is particularly useful for individuals who need assistance in building and maintaining social relations. In some studies, the skillset training have been enhanced through peer learning and reflection [55, 56].

Network diagnostics

Few studies formally used network structure in the intervention. Studies varied by using network maps as reflective tools and conversation facilitators, [51, 52, 55] to the deliberate use of network analysis as a diagnostic tool [57, 58]. Few social network interventions in our study made any deliberate attempt to alter network structure. The GROW intervention, with its emphasis on connecting isolates to other group members and connecting clusters together is an exception [57, 58].

Promoting network engagement

Engagement of influential actors in the process of network-building was used in some studies. In individual-level interventions, this was accomplished by inclusion of significant network members (e.g. caregivers, immediate family) in the sessions [50, 53, 57, 58]; and in group-level interventions by matching novices with experts or isolates with central actors [57, 58]. Such strategies formally incorporate social influence and opinion-leadership in the network-building strategy.

Goal setting, feedback, and update

Most of the included studies recognized the gradual process of network-building and the possibility of trial-and-error. Brief and short-term interactions are less likely to lead to sustainable network building. Consequently, incorporating this iterative and reflective process into interventions is an important consideration in designing network-building strategies that applies to all key elements introduced in Fig 2. Setting and updating goals based on feedback allows for individuals and groups to be actively engaged in network-building, leading to more promising network outcomes.

Since structural, social, interpersonal, and intrapersonal factors contribute to social isolation and loneliness [59], different components of network-building interventions (e.g. mapping, self-reflection, and creating networking opportunities) might be helpful within different contexts. Mapping, reflection, and maintenance of existing networks could be more helpful when existing ties have untapped potential. However, when existing networks are limited, overburdened, or lack the capacity to provide needed support, individuals might need to expand their networks by building ties with new contacts.

Networks as outcomes

Very few studies of interventions to address loneliness/isolation measure the structure of social networks. Even though included studies collected data on the structure of networks, their reported outcomes were mostly limited to basic measures, such as network size, or relative centrality of actors in the network. We did not find any study that assessed if and how interventions would affect the density, clustering, and reciprocity of relations, and whether their effect would focus on certain types of relations, or certain social circles (e.g. family, or intimate relations). Much of the literature assumes that the goal of intervention is to form links with individuals, who may then offer increased social support. This effectively (and sometimes explicitly) draws on a paradigm in which an individual’s direct connections to friends and family bring various kinds of social support, most often emotional or instrumental [60]. This is somewhat disappointing, because social network structure matters beyond the simple number of connections. There is evidence that network reciprocity encourages information diffusion [61]; and individuals find clustered networks, those with multiple closed triads, to be more supportive [62]. Clustered social networks, which include closed triads in which three people all know each other, are more supportive and more powerfully influence individuals than networks with more open triads [62, 63]. The quality of social network connections is also of concern [64]. For example, it seems that network structure and quality could be easily addressed in a program such as Genie [51], and based on the authors’ description of the program, it appears to be quite feasible to implement through online audio/video platforms such as Skype or Zoom.

Additionally, studies have not addressed the time over which network changes following intervention can be expected to endure. Interventions that strengthen relationships within existing subgroups, and provide support for their sustainment might be especially promising for reducing isolation.

Implications for post-COVID19 social relations

COVID19 pandemics and its lock-down and “social distancing” consequences worsened, and yet raised attention to the widespread problem of loneliness and its impacts on mental and physical health, particularly in older adults and vulnerable populations [6569]. To fight against the spread of COVID-19 in the communities, countries worldwide took measures, such as social distancing, stay-at-home, shelter-in-place orders, and restricting visits to residential facilities (e.g., nursing homes) [70]. The “COVID-19 connectivity paradox” posited that factors improving social connectedness seem to increase the risk of COVID-19 exposure among populations vulnerable to the negative impact of the pandemic as well social isolation [71]. Even with the new hopes invoked by the widespread administration of vaccines, the likelihood of new mutations and upcoming seasonal waves will limit many natural opportunities for face-to-face social communication and network-building for the time being.

Network-building interventions to mitigate loneliness in individuals most in need should consequently be adapted to the new context, and to balance the need for safety and connectedness [71]. Many of these key elements could be implemented online and the trainings and preparations do not seem to be heavily burdensome for health care systems. In this scoping review, we developed a conceptual framework for various potential components of network-building interventions (Fig 2), and discussed various strategies applied in interventional studies to operationalize them. Even though this review does not synthesize the evidence of effectiveness of intervention components and potential synergistic effects of their combinations, we argue that our framework can provide guidance for intervention developers to decisively choose and mix intervention components to develop potentially effective interventions that work, even if some components are not as feasible or as effective as pre-COVID19 conditions. Our review can provide practical insights into the design and implementation of network-building interventions and potential considerations in adapting them to the needs of different target groups. In Fig 2, we summarized potential opportunities and barriers to the implementation of each key element of network-building interventions.

Since the early stages of the COVID19 pandemic and in subsequent months, many health care systems adopted various telehealth care models [72, 73], so individuals connected to institutional or community services still, at least partially, benefit from their ties with professionals and staff virtually. In other words, social workers, home health aides, and other professionals connected to populations at risk of social isolation and loneliness may be well-positioned to conduct network interventions. Their assistance is particularly valuable to people without natural connections within a household (e.g. widowed older adults). For instance, staff and volunteers in programs such as Meals on Wheels serving homebound older adults, are an obvious place to start. Consumers of such formal services could then suggest other peers who might benefit, leading to a snowball sample. Community-based programs have also been found to enhance the neighborhood social networks of older adults, potentially mitigating the risk for social isolation and loneliness [26]. Another possibility to expand social networks is to leverage the skills of paraprofessionals or even volunteers, rather than clinicians, as is done in self-help groups. While the successful Network Support program uses clinicians to facilitate the integration of recovering alcoholics into networks of sober peers [74], twelve-step programs have accomplished the task for decades with and without professional assistance [75]. There are also programs that teach individuals’ trusted natural ties, family and friends, to deliver social network interventions [25, 55]. The phrase, “Each one teach one,” could easily be modified to, “Each one reach one.”

Although virtual interactions may not completely replace the benefits of in-person contacts, studies demonstrated that older adults who maintained a similar level of virtual social interaction (e.g., social media, phone) with people outside of the household had lower levels of depressive symptoms than those who increased or reduced their virtual interactions during the COVID-19 pandemic [76]. One plausible explanation is that maintaining similar levels of virtual connections allows individuals to receive support without feeling overwhelmed by the stress and worry about the pandemic, which can also be delivered through social networks [76]. Since structural, social, interpersonal, and intrapersonal factors contribute to social isolation and loneliness [59], different components of network-building interventions (e.g. mapping, self-reflection, and creating networking opportunities) might be helpful within different contexts. Mapping, reflection, and maintenance of existing networks could be more helpful when existing ties have untapped potential.

Scalability is an issue with a number of the social network interventions identified in our review. Not surprisingly, a number of the interventions were developed and tested using clinicians, who may be prohibitively expensive during a large-scale crisis. If scale is a challenge for interventions that focus on helping individuals to map and understand their networks, interventions that create groups for isolated individuals can forge connections without needing a facilitator. However, these interventions might be limited during social distancing. One possibility is to create groups online based on common interests. It might also be possible to construct micro-groups of three or four who would meet face to face either regularly or occasionally while practicing safe social distancing [56].

Limitations

We recognize that the studies included in this review were drawn from a larger study examining social network interventions across all levels (e.g., individuals, groups, communities, organizations). Thus, there may be additional strategies to support network building (e.g., interventions targeting larger communities and organizations) that were omitted from the present findings. Furthermore, due to the dearth of research that examines social network intervention outcomes, we focused on providing a picture of the typology and common elements of network-building interventions, rather than quality appraisal and synthesis of effectiveness, that could enhance the interpretability of our findings, and only relied on authors’ statements on the effectiveness of interventions. The majority of these studies relied on uncontrolled research designs limiting our understanding of the effectiveness of these interventions, underscoring the need for more rigorous trials.

Conclusions

Network-building interventions to address social isolation/loneliness have different combinations of five key elements: (1) creating opportunities for networking and socialization, (2) building social skills, (3) informing the interventions by network analysis of personal and group networks, (4) engagement of influential network members, and (5) goals setting, feedback, and update. The choice of intervention elements is a decision that should be made in light of the nature of the social relations, characteristics of participants, expertise of the facilitators, and contextual factors (such as access to online communication resources, availability of local services, willingness and accessibility of network members). Little has been done to assess how network-building interventions actually change the structure of social networks, beyond simply the number of contacts. Future studies should focus on assessing the effect of intervention elements and their combinations, and the effect of interventions on network structural outcomes.

In the midst of COVID19 pandemic, we are in urgent need of innovative approaches for building and maintaining social networks among those at risk for social isolation and loneliness. Online interventions or a combination of online, phone, and in-person interventions may facilitate network building among vulnerable individuals and groups. Alternative forms of delivery (e.g. phone or mail) might be helpful for people with limited access to the internet. The main motivation to connect through group-level interventions could vary from commonalities in the neighborhood, demographics, and common health conditions. Given the limited opportunities for group activities in online environments, specific attention should be paid to feasibility testing and adaptation. Attention should be paid to motivating and maintaining social engagement in the group context. Individual and group-level interventions should be delivered in stepwise, iterative, and reflective styles. More studies are needed to identify what combination of network-building elements works best under what conditions. Until very recently it seemed that there would be time to slowly build the evidence base to address the increasing problem of loneliness. The current COVID19 pandemic will hopefully force researchers to speed up that timetable.

Supporting information

S1 Appendix. SCOPUS search strategy.

(DOCX)

Acknowledgments

The authors thank Elena Navarro for her assistance in data screening and extraction.

Data Availability

All relevant data are within the paper and its Supporting information files.

Funding Statement

The author(s) received no specific funding for this work.

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Individual- and Group-Level Network-Building Interventions to Address Social Isolation and Loneliness; A Scoping Review with implications for COVID19

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Reviewers' comments:

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Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Partly

**********

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: N/A

Reviewer #2: N/A

**********

3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #2: Yes

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: Yes

**********

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Dear authors

The scoping review is completed in a rigorous and comprehensive manner, and in the most part, conforms to PRISMA guidelines for reporting of scoping reviews. Below are some elements that should be clarified for the readership:

Some minor typos / problems with sentence structure

Page 3

1. (introduction) – do you mean physical and mental health (rather than ‘health and mental health), or particularly mental health?

2. “ and usually provide a single scale”. Do you mean single score? Please clarify.

3. “…in respondent’s social network [25]”. Do you mean in a respondent’s social network OR in respondents’ social networks??

Page 5

4. “We followed PRISMA-ScR guidelines for scoping reviews in the conduct of the literature review, data extraction/charting, and synthesis [48]” – is this clearer?

Page 7

5. “Three studies explicitly incorporated the practice of? analyzing network structure into their interventions. Or ‘…. The analysis of network structure….?

Page 9

6. P ? states “Network structural and quality considerations could easily be implemented in a program such as Genie [54], and are quite amenable to online audio/video platforms such as Skype or Zoom”. Is it their assessment that is amenable to an online platform? Please clarify this sentence.

Other minor clarifications necessary

7. How many reviewers / pairs of reviewers were there? Was there screening for duplicates? Were there any disagreements and how were there resolved – for each stage of the full screening process /study selection?

8. Was a quality appraisal conducted? Was this relevant the eh objectives of the review? There is a mention of quality of studies in the discussion.

9. Summarise what categories of data was extracted from studies (in methods section)

Mores substantial changes necessary:

10. The rationale and particularly the objectives of the review aren’t very clear. This does map onto the requirements of the prisma guidelines. The following statement (p5) indicates which articles are the focus of the scoping review, but what is the point of the review / review questions? Is it to map this literature? To identify specific intervention components?

“We conducted a systematic scoping review of studies that assessed how social network interventions that address loneliness and isolation affect the structure of social networks. We evaluated how these interventions can be adapted to promote connectedness in the wake of COVID19.” (p5)

11. In summarising the results, it is not clear whether the interventions described are in-person or not. Band et al (2019) is described as an online platform, delivered in person. Are all others also in-person? Given the links to the covid context (delivery of virtual / online services), these characteristics are important to include.

12. The outcomes / effectiveness / impact has not been summarised for all the studies mentioned in the narrative. Were they effective / have impact on social networks (or elements of)? For example, in the following narrative, only the outcomes of the Tesdahl (2015) study are described. It may be helpful to summarise briefly the effectiveness (as reported by the authors of the primary papers) of other studies. This is also relevant given the comment made by the review authors that “In the face of COVID 19, it is critical to consider the factors that facilitate or impede the potential use of social network interventions to alleviate social isolation and loneliness”. Why have the results of some of the studies been summarised, but not others, and are there implications around quality of the studies?

“van Asselt-Goverts et al. (2018) [58] reported the size, frequency, and functional characteristics of social relations to important social roles (family, friends, colleagues, neighbors, others). Only Gesell et al. (2013)[60] studied change in network structure and descriptively reported the change in structural measures (e.g. density, reciprocity, clustering, isolates, etc.) over time. Kasari et al. (2016)[53] reported social network salience scores (see above). Tesdahl 8 (2015)[59] developed an exponential random graph model to assess how personal, interpersonal, and structural features of the network was associated with existence of ties between pairs of actor. The model showed that the total number of sessions that pairs of participants attended, as well as similarity in physical activity and pregnancy due date would significantly increase the chance that they are connected in the conversation network. However, they did not directly assess the effect of the intervention, since there were no parallel control group or longitudinal assessment of network formation.”

13. The beginning of the discussion states that “Our review identified multiple interventions that may mitigate social isolation and loneliness among vulnerable individuals and groups”. Related to the point 11 above, it is not clear from the summary of results which interventions were effective. Also, were the interventions included in the review all targeted at vulnerable groups? What types of ‘vulnerable’ groups? Was there any eligibility criteria about the interventions being provided to vulnerable groups?

14. It is important that the review authors provide more context around the covid19 situation (for e.g. isolating, shielding, particularly of vulnerable groups, closure of social / community groups and facilities) so that the reader can understand why specific intervention components are relevant to the covid 19 situation.

15. Related to 15 (above) the context of social distancing / lockdown isn’t fully discussed. One consideration (which the authors have mentioned) is how these intervention can be ‘delivered’ by HCPs, with/without facilitators, or even virtually. But another important consideration is HOW the interventions will result in positive outcomes when (during covid 19) there are more limited options for face-to-face contact (particularly for vulnerable individuals). Are the authors suggesting that the users will develop/improve their networks online /on the phone etc? What are the implications of this for perceived support and loneliness, i.e. does this replicate / approximate in-person networks?

16. Finally, the authors state “In Figure 2, we present potential opportunities and barriers to implementation of each key element of network-building interventions”. It isn’t obvious to me how the figure presents opportunities and barriers to implementation of each key element… Can this be explained further?

Reviewer #2: This is an interesting paper but it could be improved by fleshing out what are the outcomes of the interventions reviewed in relation to social isolation and loneliness. The paper could engage in a more narrative style that highlights the implications of those findings. Some information about the characteristics of the samples in the interventions would be useful as well, as research has showed that people's social networks differ along the life course (i.e. regarding quantity and quality).

Additional comments:

It is not describe how the authors went from 3390 references to assess 233.

p.13 -- Student??. Did the author mean studies rather than students?

There is not much discussion about the effectiveness of the interventions (and for whom were effective).

**********

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Reviewer #1: No

Reviewer #2: No

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

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Attachment

Submitted filename: PONE-D-20-26180_reviewer.pdf

PLoS One. 2021 Jun 25;16(6):e0253734. doi: 10.1371/journal.pone.0253734.r002

Author response to Decision Letter 0


11 May 2021

Dear esteemed editors and reviewers of PLOS ONE,

Thank you for thorough assessment of our manuscript, titled “Individual- and Group-Level Network-Building Interventions to Address Social Isolation and Loneliness; A Scoping Review with implications for COVID19”. We tired our best to address reviewers’ comments. Please find attached, the point-by-point response to the reviews. We highlighted the sections that are revised to address suggested revisions, in yellow in the track-changed version of the manuscript.

Looking forward to your positive consideration.

Reza Yousefi Nooraie

________________________________________

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Dear authors

The scoping review is completed in a rigorous and comprehensive manner, and in the most part, conforms to PRISMA guidelines for reporting of scoping reviews. Below are some elements that should be clarified for the readership:

Some minor typos / problems with sentence structure

Page 3

1. (introduction) – do you mean physical and mental health (rather than ‘health and mental health), or particularly mental health?

Corrected.

2. “ and usually provide a single scale”. Do you mean single score? Please clarify.

Corrected.

3. “…in respondent’s social network [25]”. Do you mean in a respondent’s social network OR in respondents’ social networks??

Corrected.

Page 5

4. “We followed PRISMA-ScR guidelines for scoping reviews in the conduct of the literature review, data extraction/charting, and synthesis [48]” – is this clearer?

Thank you. Corrected.

Page 7

5. “Three studies explicitly incorporated the practice of? analyzing network structure into their interventions. Or ‘…. The analysis of network structure….?

Corrected.

Page 9

6. P ? states “Network structural and quality considerations could easily be implemented in a program such as Genie [54], and are quite amenable to online audio/video platforms such as Skype or Zoom”. Is it their assessment that is amenable to an online platform? Please clarify this sentence.

This is our interpretation of the intervention, based on the information provided in the included papers. We revised the sentence for clarity.

Other minor clarifications necessary

7. How many reviewers / pairs of reviewers were there? Was there screening for duplicates? Were there any disagreements and how were there resolved – for each stage of the full screening process /study selection?

We calibrated our screening and data extractions on a sample of papers that were independently reviewed by pairs of reviewers. However, information from included studies were extracted by a single reviewer. The group regularly met to discuss and resolve uncertainties and potential disagreements, and continuously updated the data-charting form. We added clarification to this section.

8. Was a quality appraisal conducted? Was this relevant to the objectives of the review? There is a mention of quality of studies in the discussion.

Consistent with the common practice of scoping reviews, we focused on providing a picture of common elements of network-building interventions, rather than quality appraisal and synthesis of effectiveness.

This section was provided in the Limitations section.

9. Summarise what categories of data was extracted from studies (in methods section)

We added the following to the Methods section:

For each included study, we extracted information pertaining to the study settings, characteristics of network actors, the nature of network relations, characteristics of the intervention(s), theoretical underpinnings of the intervention(s) according to the authors, measures of network change, and the effectiveness of the intervention according to the authors.

Mores substantial changes necessary:

10. The rationale and particularly the objectives of the review aren’t very clear. This does map onto the requirements of the prisma guidelines. The following statement (p5) indicates which articles are the focus of the scoping review, but what is the point of the review / review questions? Is it to map this literature? To identify specific intervention components?

“We conducted a systematic scoping review of studies that assessed how social network interventions that address loneliness and isolation affect the structure of social networks. We evaluated how these interventions can be adapted to promote connectedness in the wake of COVID19.” (p5)

We revised the aims of the study as follows: “we conducted a systematic scoping review of studies assessing the effect of interventions to address loneliness and social isolation on the structure of social networks. We aimed to map the types and components of these interventions and methods/metrics of assessing changes in social networks.”

11. In summarising the results, it is not clear whether the interventions described are in-person or not. Band et al (2019) is described as an online platform, delivered in person. Are all others also in-person? Given the links to the covid context (delivery of virtual / online services), these characteristics are important to include.

Thank you. We added a section to Table 1, indicating the intervention level.

12. The outcomes / effectiveness / impact has not been summarised for all the studies mentioned in the narrative. Were they effective / have impact on social networks (or elements of)? For example, in the following narrative, only the outcomes of the Tesdahl (2015) study are described. It may be helpful to summarise briefly the effectiveness (as reported by the authors of the primary papers) of other studies. This is also relevant given the comment made by the review authors that “In the face of COVID 19, it is critical to consider the factors that facilitate or impede the potential use of social network interventions to alleviate social isolation and loneliness”. Why have the results of some of the studies been summarised, but not others, and are there implications around quality of the studies?

“van Asselt-Goverts et al. (2018) [58] reported the size, frequency, and functional characteristics of social relations to important social roles (family, friends, colleagues, neighbors, others). Only Gesell et al. (2013)[60] studied change in network structure and descriptively reported the change in structural measures (e.g. density, reciprocity, clustering, isolates, etc.) over time. Kasari et al. (2016)[53] reported social network salience scores (see above). Tesdahl 8 (2015)[59] developed an exponential random graph model to assess how personal, interpersonal, and structural features of the network was associated with existence of ties between pairs of actor. The model showed that the total number of sessions that pairs of participants attended, as well as similarity in physical activity and pregnancy due date would significantly increase the chance that they are connected in the conversation network. However, they did not directly assess the effect of the intervention, since there were no parallel control group or longitudinal assessment of network formation.”

The aim of this scoping review was to provide an overall picture of current research in the fields, and not to synthesize the results of the included studies (as stated in the limitations). However, to provide a preliminary depiction of study findings we added a column to Table 1 indicating the findings, and expanded the ‘outcomes’ section of the Results to provide a summary of the evidence of effectiveness of the intervention as presented in each study.

13. The beginning of the discussion states that “Our review identified multiple interventions that may mitigate social isolation and loneliness among vulnerable individuals and groups”. Related to the point 11 above, it is not clear from the summary of results which interventions were effective.

We did not change this section, since we provided more details about the study findings in the Results and Table 1.

Also, were the interventions included in the review all targeted at vulnerable groups? What types of ‘vulnerable’ groups? Was there any eligibility criteria about the interventions being provided to vulnerable groups?

Our eligibility criteria were limited to studies using network interventions to address loneliness/social isolation. We did not intentionally limit the studies to vulnerable populations. But given the nature of the study outcome, most included studies were focused on vulnerable individuals.

14. It is important that the review authors provide more context around the covid19 situation (for e.g. isolating, shielding, particularly of vulnerable groups, closure of social / community groups and facilities) so that the reader can understand why specific intervention components are relevant to the covid 19 situation.

15. Related to 15 (above) the context of social distancing / lockdown isn’t fully discussed. One consideration (which the authors have mentioned) is how these intervention can be ‘delivered’ by HCPs, with/without facilitators, or even virtually. But another important consideration is HOW the interventions will result in positive outcomes when (during covid 19) there are more limited options for face-to-face contact (particularly for vulnerable individuals). Are the authors suggesting that the users will develop/improve their networks online /on the phone etc? What are the implications of this for perceived support and loneliness, i.e. does this replicate / approximate in-person networks?

We expanded the Discussion and provided further rationale and contextual information for post-COVID social contexts. As indicated in the Discussion: Even though this review does not synthesize the evidence of effectiveness of intervention components and potential synergistic effects of their combinations, we argue that our framework can provide a guidance for intervention developers to decisively choose and mix intervention components to develop potentially effective interventions that work, even if some components are not as feasible or as effective as pre-COVID19 conditions.

16. Finally, the authors state “In Figure 2, we present potential opportunities and barriers to implementation of each key element of network-building interventions”. It isn’t obvious to me how the figure presents opportunities and barriers to implementation of each key element… Can this be explained further?

Thank you for bringing this up. This statement referred to a more detailed version of the Figure that is now included in the manuscript

Reviewer #2: This is an interesting paper but it could be improved by fleshing out what are the outcomes of the interventions reviewed in relation to social isolation and loneliness.

The paper could engage in a more narrative style that highlights the implications of those findings.

We expanded the Discussion to provide a clear rationale for and potential implications of the conceptual framework we developed (presented in Figure 2). The Figure also includes implications and barriers related to post-COVID19 social contexts.

Some information about the characteristics of the samples in the interventions would be useful as well, as research has showed that people's social networks differ along the life course (i.e. regarding quantity and quality).

Table 1 now includes more detailed description of participant characteristics and demographics.

Additional comments:

It is not describe how the authors went from 3390 references to assess 233.

We added more details to the PRISMA diagram (Figure 1). Given the complexity of the field of network research and the lack of widely used terminologies, we excluded the majority of records at the abstract screening phase due to obvious lack of relevance to social networks (e.g. studying genomic, neural, or animal networks), irrelevance to social isolation/loneliness (e.g. studies of collaboration, advice, or friendship networks), or lack of interventional components (e.g. observational studies of the structure of networks, or their natural emergence over time).

p.13 -- Student??. Did the author mean studies rather than students?

The two mentioned studies were on school children. We changed the word ‘student’ to ‘individual’ to prevent confusion.

There is not much discussion about the effectiveness of the interventions (and for whom were effective).

The aim of this scoping review was to provide an overall picture of current research in the fields, and not to synthesize the results of the included studies (as stated in the limitations). However, to provide a preliminary depiction of study findings we added a column to Table 1 indicating the findings, and expanded the ‘outcomes’ section of the Results to provide a summary of the evidence of effectiveness of the intervention as presented in each study.

Attachment

Submitted filename: response to reviewers.docx

Decision Letter 1

Noleen McCorry

14 Jun 2021

Individual- and Group-Level Network-Building Interventions to Address Social Isolation and Loneliness; A Scoping Review with implications for COVID19

PONE-D-20-26180R1

Dear Dr. Yousefi Nooraie,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

In the spirit of transparency I want to inform you that I was also one of the reviewers of your manuscript.

An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Noleen McCorry

Guest Editor

PLOS ONE

Additional Editor Comments (optional):

Reviewers' comments:

Acceptance letter

Noleen McCorry

17 Jun 2021

PONE-D-20-26180R1

Individual- and group-level network-building interventions to address social isolation and loneliness; a scoping review with implications for COVID19

Dear Dr. Yousefi Nooraie:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Noleen McCorry

Guest Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 Appendix. SCOPUS search strategy.

    (DOCX)

    Attachment

    Submitted filename: PONE-D-20-26180_reviewer.pdf

    Attachment

    Submitted filename: response to reviewers.docx

    Data Availability Statement

    All relevant data are within the paper and its Supporting information files.


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