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[Preprint]. 2022 Aug 9:2022.08.08.22278543. [Version 1] doi: 10.1101/2022.08.08.22278543

Post-acute sequelae of SARS-CoV-2 (PASC) impact quality of life at 6, 12 and 18 months post-infection

Zoe O Demko, Tong Yu, Sarika K Mullapudi, M Gabriela Varela Heslin, Chamia A Dorsey, Christine B Payton, Jeffrey A Tornheim, Paul W Blair, Shruti H Mehta, David L Thomas, Yukari C Manabe, Annukka AR Antar; the OutSMART Study Team
PMCID: PMC9387157  PMID: 35982674

Abstract

Little data exist on long COVID outcomes beyond one year. In a cohort enrolled with mild-moderate acute COVID-19, a wide range of symptoms manifest at 6, 12, and 18 months. Endorsing over 3 symptoms associates with poorer quality of life in 5 domains: physical, social, fatigue, pain, and general health.

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