Skip to main content
Cells logoLink to Cells
. 2022 Aug 22;11(16):2609. doi: 10.3390/cells11162609

Correction: Lee et al. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells 2022, 11, 364

Jinwoo Lee 1, Subin An 2,3, Sang-Jin Lee 1,*, Jong-Sun Kang 2,3,*
PMCID: PMC9406313  PMID: 36010695

The authors wish to make the following corrections to this paper [1]:

For Table 1, reference [1] has been changed to [64]; reference [2] has been changed to [72]; reference [3] has been changed to [73]; reference [4] has been changed to [82]; reference [5] has been changed to [123]; reference [6] has been changed to [83]; reference [7] has been changed to [92]; reference [8] has been changed to [95]; reference [9] has been changed to [98]. The corrected Table 1 showed as below:

Table 1.

Effect of targeting PRMTs on NMD phenotypes.

PRMT Method Model Effect on NMD Phenotype
General methyltransferase inhibitor AdOx Hela cells Rescues nuclear import of FUS mutants (R524S, R522G, R525L) [64]
General methyltransferase inhibitor AdOx Primary rat hippocampal neurons Rescues nuclear import of FUS mutant (P525L) [64]
General methyltransferase inhibitor AdOx Primary motor neurons Diminishes cytoplasmic FUS mutants (R521H, R521G, R521C) [72]
General methyltransferase inhibitor AdOx ALS patient-derived lymphoblastoid cells Rescues nuclear import of FUS mutant (R518G) [73]
PRMT1 siRNA KD Hela cells Partial rescue of nuclear import of FUS mutant (P525L) [64]
PRMT1 KO MEF Diminishes cytoplasmic FUS mutants (R521H, R521G, R521C) [72]
PRMT1 siRNA KD HEK293 Diminishes cytoplasmic FUS mutants (R521H, R521G, R521C) [72]
PRMT1 siRNA KD Primary motor neurons Increases cytoplasmic FUS mutants (R521H, R521G, R521C) [72]
PRMT1 Inhibitor (AMI-1) ALS patient-derived lymphoblastoid cells Rescues nuclear import of FUS mutant (R518G) [73]
PRMT1 shRNA KD Cortical neurons Enhances neurite shortening by FUS-R521C under oxidative stress [82]
PRMT1 Overexpression Cortical neurons Prevents neurite shortening by FUS-R521C under oxidative stress [82]
PRMT1 Inhibitor (MS023) NSC-34 Abrogates PR15-induced toxicity [123]
DART1
(PRMT1/PRMT8 ortholog)
siRNA KD Drosophila Enhances neurodegeneration of eyes induced by wild-type FUS or FUS-R521H [73]
DART1
(PRMT1/PRMT8 ortholog)
siRNA KD Drosophila Enhances neurodegeneration of eyes induced by wild-type FUS or FUS-P525L [83]
PRMT5 Inhibitor (CMP5 or HLCL65) Mouse memory T cells Suppresses memory T cell expansion [92]
PRMT5 Inhibitor (CMP5) or shRNA KD Human memory T cells Suppresses memory T cell activation and expansion, partly through downregulation of IL-2 [92]
PRMT5 Inhibitor (CMP5) OVA-induced DTH mouse Suppresses T cell-mediated inflammatory response [92]
PRMT5 Inhibitor (HLCL65) MOG-induced EAE mouse Suppresses clinical signs of EAE through diminishing T cell-mediated inflammatory response [92]
PRMT5 CD4+ T-cell specific KO MOG-induced EAE mouse Suppresses clinical signs of EAE through diminishing T cell-mediated inflammatory response [95]
PRMT6 Overexpression MN-1 Exacerbates cytotoxicity due to polyglutamine-expanded AR [98]
DART8
(PRMT6 ortholog)
RNAi KD Drosophila Suppresses neurodegenerative phenotype due to polyglutamine-expanded AR [98]

The authors apologize for any inconvenience caused and state that the scientific conclusions are unaffected. The original publication has also been updated.

Footnotes

Publisher’s Note: MDPI stays neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Reference

  • 1.Lee J., An S., Lee S.-J., Kang J.-S. Protein Arginine Methyltransferases in Neuromuscular Function and Diseases. Cells. 2022;11:364. doi: 10.3390/cells11030364. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Cells are provided here courtesy of Multidisciplinary Digital Publishing Institute (MDPI)

RESOURCES