Unusual Regulation of Splicing of the Cholinergic Locus in Caenorhabditis elegans

Files in this data supplement:

  • Supporting Information: Figures S1-S5, File S1, and Table S1 (PDF, 1 MB)
  • Figure S1: Complementary R1 elements from the cholinergic loci of eight Caenorhabditis species. (PDF, 495 KB)
  • Figure S2: Complementary R2 elements from the cholinergic loci of eight Caenorhabditis species. (PDF, 459 KB)
  • Figure S3: Genomic structures of the cholinergic loci in Globodera pallida and Meloidogyne hapla, two nematode species with an abundance of UNC-17 exons. (PDF, 387 KB)
  • Figure S4: Putative stem-loop alignments of the R1-like and R2-like sequences from the cholinergic loci of Globodera pallida and Meloidogyne hapla (see Figure S3). (PDF, 423 KB)
  • Figure S5: Putative stem-loop alignments of the R1-like (red) and R2-like (blue) sequences from the cholinergic loci of representative species from three different animal phyla (these are in addition to the species presented in Figure 6). (PDF, 444 KB)
  • File S1: Supporting Materials and Methods (PDF, 380 KB)
  • Table S1: Properties and evaluation of C. elegans R1 and R2 sequences. (PDF, 374 KB)