Skip to main content
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1985 Apr;44(4):273–276. doi: 10.1136/ard.44.4.273

Is amyloid A (AA) amyloidosis always secondary?

C P Maury, T Törnroth, O Wegelius
PMCID: PMC1001626  PMID: 3985695

Abstract

The case is reported of a patient with systemic AA amyloidosis associated with non-specific mesenteric lymphadenitis and chronic sideropenia. Renal, small bowel, and rectal biopsies showed amyloid deposits containing AA protein, as defined by potassium permanganate sensitivity and by reactivity with AA antiserum. Reversal of the nephrotic syndrome occurred during steroid-azathioprine therapy.

Full text

PDF
275

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brow J. R., Parker F., Weinstein W. M., Rubin C. E. The small intestinal mucosa in dermatitis herpetiformis. I. Severity and distribution of the small intestinal lesion and associated malabsorption. Gastroenterology. 1971 Mar;60(3):355–361. [PubMed] [Google Scholar]
  2. Garcia-SanMiguel J., Rozman C., Palacin A., Nomdedeu B. Mesenteric hyaline plasma cell lymph node hyperplasia with amyloid deposits. Arch Intern Med. 1981 Feb;141(2):261–263. [PubMed] [Google Scholar]
  3. Glenner G. G. Amyloid deposits and amyloidosis: the beta-fibrilloses (second of two parts). N Engl J Med. 1980 Jun 12;302(24):1333–1343. doi: 10.1056/NEJM198006123022403. [DOI] [PubMed] [Google Scholar]
  4. Maury C. P., Teppo A., Eklund B., Ahonen J. Serum amyloid A protein: a sensitive indicator of renal allograft rejection in humans. Transplantation. 1983 Nov;36(5):501–504. [PubMed] [Google Scholar]
  5. Michael J., Jones N. F. Spontaneous remissions of nephrotic syndrome in renal amyloidosis. Br Med J. 1978 Jun 17;1(6127):1592–1593. doi: 10.1136/bmj.1.6127.1592. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Pilon V. A., Gomez L. G., Butler J. J. Systemic amyloidosis associated with a benign mesenteric lymphoid mass. Am J Clin Pathol. 1982 Jul;78(1):112–116. doi: 10.1093/ajcp/78.1.112. [DOI] [PubMed] [Google Scholar]
  7. Pras M., Zaretzky J., Frangione B., Franklin E. C. AA protein in a case of "primary" or "idiopathic" amyloidosis. Am J Med. 1980 Feb;68(2):291–294. doi: 10.1016/0002-9343(80)90369-1. [DOI] [PubMed] [Google Scholar]
  8. Wright J. R., Calkins E., Humphrey R. L. Potassium permanganate reaction in amyloidosis. A histologic method to assist in differentiating forms of this disease. Lab Invest. 1977 Mar;36(3):274–281. [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES