Skip to main content
PMC home page
Annals of the Rheumatic Diseases logoLink to Annals of the Rheumatic Diseases
. 1977 Apr;36(2):152–156. doi: 10.1136/ard.36.2.152

Involvement of the eye in SLE and scleroderma. A study using fluorescein angiography in addition to clinical ophthalmic assessment.

D M Grennan, J Forrester
PMCID: PMC1006650  PMID: 856066

Abstract

General examination of the eye was carried out in 22 patients with systemic lupus erythematosus (SLE) and in 10 with scleroderma. 3 of the SLE and 2 of the scleroderma patients had keratoconjunctivitis sicca. Fluorescein angiography showed abnormalities of the retinal vasculature in one of a subgroup of 12 SLE patients and one of 10 scleroderma patients. None of the 12 SLE patients had abnormalities of the choroidal vasculature, while 5 of the 10 scleroderma patients had patchy areas of nonperfusion of the choroidal capillary bed.

Full text

PDF
155

Images in this article

154Image
on p.154
154Image
on p.154
155Image
on p.155
155Image
on p.155

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alarcón-Segovia D., Ibánez G., Hernández-Ortíz J., Velázquez-Forero F., González-Jiménez Y. Sjögren's syndrome in progressive systemic sclerosis (scleroderma). Am J Med. 1974 Jul;57(1):78–85. doi: 10.1016/0002-9343(74)90771-2. [DOI] [PubMed] [Google Scholar]
  2. Ashton N., Coomes E. N., Garner A., Oliver D. O. Retinopathy due to progressive systemic sclerosis. J Pathol Bacteriol. 1968 Oct;96(2):259–268. doi: 10.1002/path.1700960202. [DOI] [PubMed] [Google Scholar]
  3. DUBOIS E. L., TUFFANELLI D. L. CLINICAL MANIFESTATIONS OF SYSTEMIC LUPUS ERYTHEMATOSUS. COMPUTER ANALYSIS OF 520 CASES. JAMA. 1964 Oct 12;190:104–111. doi: 10.1001/jama.1964.03070150014003. [DOI] [PubMed] [Google Scholar]
  4. Edmonds J. P., Bruneau C., Hughes G. R. Assessment of activity in SLE: a clinical and serological study. Ann Rheum Dis. 1975 Dec;34(6):543–544. doi: 10.1136/ard.34.6.543-b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Farkas T. G., Sylvester V., Archer D. The choroidopathy of progressive systemic sclerosis (scleroderma). Am J Ophthalmol. 1972 Nov;74(5):875–886. doi: 10.1016/0002-9394(72)91208-1. [DOI] [PubMed] [Google Scholar]
  6. Hammami H., Streiff E. B. Altérations vasculaires rétiniennes dans un cas de lupus érythémateux disséminé. Evolution après traitement aux immunosuppresseurs. Ophthalmologica. 1973;166(1):16–35. doi: 10.1159/000306792. [DOI] [PubMed] [Google Scholar]
  7. Hughes G. R. Significance of anti-D.N.A. antibodies in systemic lupus erythematosus. Lancet. 1971 Oct 16;2(7729):861–863. doi: 10.1016/s0140-6736(71)90234-0. [DOI] [PubMed] [Google Scholar]
  8. Kirkham T. H. Scleroderma and Sjögren's syndrome. Br J Ophthalmol. 1969 Feb;53(2):131–133. doi: 10.1136/bjo.53.2.131. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. MANSCHOT W. A. GENERALIZED SCLERODERMA WITH OCULAR SYMPTOMS. Ophthalmologica. 1965;149:131–137. doi: 10.1159/000304743. [DOI] [PubMed] [Google Scholar]
  10. Maclean H., Guthrie W. Retinopathy in scleroderma. Trans Ophthalmol Soc U K. 1970;89:209–220. [PubMed] [Google Scholar]
  11. Norton W. L., Nardo J. M. Vascular disease in progressive systemic sclerosis (scleroderma). Ann Intern Med. 1970 Aug;73(2):317–324. doi: 10.7326/0003-4819-73-2-317. [DOI] [PubMed] [Google Scholar]
  12. POLLACK I. P., BECKER B. Cytoid bodies of the retina in a patient with scleroderma. Am J Ophthalmol. 1962 Oct;54:655–660. [PubMed] [Google Scholar]
  13. RODNAN G. P. A REVIEW OF RECENT OBSERVATIONS AND CURRENT THEORIES ON THE ETIOLOGY AND PATHOGENESIS OF PROGRESSIVE SYSTEMIC SCLEROSIS (DIFFUSE SCLERODERMA). J Chronic Dis. 1963 Aug;16:929–949. doi: 10.1016/0021-9681(63)90141-3. [DOI] [PubMed] [Google Scholar]
  14. Steinberg A. D., Talal N. The coexistence of Sjögren's syndrome and systemic lupus erythematosus. Ann Intern Med. 1971 Jan;74(1):55–61. doi: 10.7326/0003-4819-74-1-55. [DOI] [PubMed] [Google Scholar]
  15. Whaley K., Webb J., McAvoy B. A., Hughes G. R., Lee P., MacSween R. N., Buchanan W. W. Sjogren's syndrome. 2. Clinical associations and immunological phenomena. Q J Med. 1973 Jul;42(167):513–548. [PubMed] [Google Scholar]

Articles from Annals of the Rheumatic Diseases are provided here courtesy of BMJ Publishing Group

RESOURCES