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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1984 Sep;47(9):936–942. doi: 10.1136/jnnp.47.9.936

The differential diagnosis of congenital nystagmus.

M Gresty, N Page, H Barratt
PMCID: PMC1027994  PMID: 6481387

Abstract

The decision whether a nystagmus is congenital or acquired may be difficult and is of importance in patients presenting with neurological complaints. In this article, established diagnostic criteria are critically reviewed with particular emphasis on types of nystagmus waveform and their relationship to pursuit and optokinetic responses. Attention is drawn to certain acquired nystagmus which may have similar features which have hitherto been accepted as pathognomonic of congenital nystagmus. Symptoms due to congenital nystagmus are discussed and related to the oculomotor abnormalities. The importance of the characteristics of congenital nystagmus are evaluated for use in differential diagnosis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Dell'Osso L. F., Daroff R. B. Congenital nystagmus waveforms and foveation strategy. Doc Ophthalmol. 1975 Nov 21;39(1):155–182. doi: 10.1007/BF00578761. [DOI] [PubMed] [Google Scholar]
  2. Dell'Osso L., Gauthier G., Liberman G., Stark L. Eye movement recordings as a diagnostic tool in a case of congenital nystagmus. Am J Optom Arch Am Acad Optom. 1972 Jan;49(1):3–13. doi: 10.1097/00006324-197201000-00002. [DOI] [PubMed] [Google Scholar]
  3. FORSSMAN B. A STUDY OF CONGENITAL NYSTAGMUS. Acta Otolaryngol. 1964 May;57:427–449. doi: 10.3109/00016486409137104. [DOI] [PubMed] [Google Scholar]
  4. Gresty M. A., Ell J. J., Findley L. J. Acquired pendular nystagmus: its characteristics, localising value and pathophysiology. J Neurol Neurosurg Psychiatry. 1982 May;45(5):431–439. doi: 10.1136/jnnp.45.5.431. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Gresty M. A., Halmagyi G. M. Abnormal head movements. J Neurol Neurosurg Psychiatry. 1979 Aug;42(8):705–714. doi: 10.1136/jnnp.42.8.705. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Halmagyi G. M., Gresty M. A. Clinical signs of visual-vestibular interaction. J Neurol Neurosurg Psychiatry. 1979 Oct;42(10):934–939. doi: 10.1136/jnnp.42.10.934. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Halmagyi G. M., Gresty M. A., Leech J. Reversed optokinetic nystagmus (OKN): mechanism and clinical significance. Ann Neurol. 1980 May;7(5):429–435. doi: 10.1002/ana.410070507. [DOI] [PubMed] [Google Scholar]
  8. Honrubia V., Downey W. L., Mitchell D. P., Ward P. H. Experimental studies on optokinetic nystagmus. II. Normal humans. Acta Otolaryngol. 1968 May;65(5):441–448. doi: 10.3109/00016486809120986. [DOI] [PubMed] [Google Scholar]
  9. Hood J. D., Leech J. The significance of peripheral vision in the perception of movement. Acta Otolaryngol. 1974 Jan-Feb;77(1):72–79. doi: 10.3109/00016487409124600. [DOI] [PubMed] [Google Scholar]
  10. Leech J., Gresty M., Hess K., Rudge P. Gaze failure, drifting eye movements, and centripetal nystagmus in cerebellar disease. Br J Ophthalmol. 1977 Dec;61(12):774–781. doi: 10.1136/bjo.61.12.774. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. TRINCKER D., SIEBER J., BARTUAL J. [Oscillation analysis of vestibular and optokinetic eye movements and of those induced by electrical irritation. 1. Continual eye movements: frequency processes and location curves]. Kybernetik. 1961 Jan;1:21–28. doi: 10.1007/BF00293850. [DOI] [PubMed] [Google Scholar]
  12. Yee R. D., Baloh R. W., Honrubia V., Kim Y. S. A study of congenital nystagmus: vestibular nystagmus. J Otolaryngol. 1981 Apr;10(2):89–98. [PubMed] [Google Scholar]
  13. Zee D. S., Leigh R. J., Mathieu-Millaire F. Cerebellar control of ocular gaze stability. Ann Neurol. 1980 Jan;7(1):37–40. doi: 10.1002/ana.410070108. [DOI] [PubMed] [Google Scholar]

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