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. 1979 Sep;63(9):621–626. doi: 10.1136/bjo.63.9.621

An outbreak of adenovirus keratoconjunctivitis in bristol.

A B Tullo, P G Higgins
PMCID: PMC1043571  PMID: 226115

Abstract

Nineteen cases of keratoconjunctivitis caused by an adenovirus serologically related to types 10 and 19 are described. Seventeen of the patients presented over a period of 7 weeks and included 4 who were involved in a minor outbreak at a factory. The presentation and clinical features closely resembled those caused by adenoviruses types 8 and 19. Mild to severe follicular conjunctivitis, superficial punctate keratitis, discrete subepithelial opacities, membrane formation, and conjunctival scarring were all observed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barnard D. L., Hart J. C., Marmion V. J., Clarke S. K. Outbreak in Bristol of conjunctivitis caused by adenovirus type 8, and its epidemiology and control. Br Med J. 1973 Apr 21;2(5859):165–169. doi: 10.1136/bmj.2.5859.165. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Burns R. P., Potter M. H. Epidemic keratoconjunctivitis due to adenovirus type 19. Am J Ophthalmol. 1976 Jan;81(1):27–29. doi: 10.1016/0002-9394(76)90187-2. [DOI] [PubMed] [Google Scholar]
  3. Clarke S. K., Hart J. C., Barnard D. L. The disinfection of instruments and hands during outbreaks of epidemic keratoconjunctivitis. Trans Ophthalmol Soc U K. 1972;92:613–618. [PubMed] [Google Scholar]
  4. Darougar S., Quinlan M. P., Gibson J. A., Jones B. R. Epidemic keratoconjunctivitis and chronic papillary conjunctivitis in London due to adenovirus type 19. Br J Ophthalmol. 1977 Feb;61(2):76–85. doi: 10.1136/bjo.61.2.76. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Dawson C. R., Hanna L., Togni B. Adenovirus type 8 infections in the United States. IV. Observations on the pathogenesis of lesions in severe eye disease. Arch Ophthalmol. 1972 Mar;87(3):258–268. doi: 10.1001/archopht.1972.01000020260005. [DOI] [PubMed] [Google Scholar]
  6. Dawson C. R., Hanna L., Wood T. R., Despain R. Adenovirus type 8 keratoconjunctivitis in the United States. 3. Epidemiologic, clinical, and microbiologic features. Am J Ophthalmol. 1970 Mar;69(3):473–480. doi: 10.1016/0002-9394(70)92285-3. [DOI] [PubMed] [Google Scholar]
  7. Desmyter J., De Jong J. C., Slaterus K. W., Verlaeckt H. Letter: Keratoconjunctivitis caused by Adenovirus Type 19. Br Med J. 1974 Nov 16;4(5941):406–406. doi: 10.1136/bmj.4.5941.406. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Dudgeon J., Bhargava S. K., Ross C. A. Treatment of adenovirus infection of the eye with 5-iodo-2'-deoxyuridine. A double-blind trial. Br J Ophthalmol. 1969 Aug;53(8):530–533. doi: 10.1136/bjo.53.8.530. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. GRAYSTON J. T., YANG Y. F., JOHNSTON P. B., KO L. S. EPIDEMIC KERATOCONJUNCTIVITIS ON TAIWAN: ETIOLOGICAL AND CLINICAL STUDIES. Am J Trop Med Hyg. 1964 May;13:492–498. doi: 10.4269/ajtmh.1964.13.492. [DOI] [PubMed] [Google Scholar]
  10. HUEBNER R. J., ROWE W. P. Adenoviruses as etiologic agents in conjunctivitis and keratoconjunctivitis. Am J Ophthalmol. 1957 Apr;43(4 Pt 2):20–25. doi: 10.1016/0002-9394(57)91470-8. [DOI] [PubMed] [Google Scholar]
  11. Hart J. C., Barnard D. L., Clarke S. K., Marmion V. J. Epidemic keratoconjunctivitis. A virological and clinical study. Trans Ophthalmol Soc U K. 1972;92:795–801. [PubMed] [Google Scholar]
  12. Higgins P. G., Scott R. J. The isolation of enteroviruses from cases of acute conjunctivitis. J Clin Pathol. 1973 Sep;26(9):706–711. doi: 10.1136/jcp.26.9.706. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. JAWETZ E., KIMURA S. J., HANNA L., COLEMAN V. R., THYGESON P., NICHOLAS A. Studies on the etiology of epidemic keratoconjunctivitis. Am J Ophthalmol. 1955 Nov;40(5 Pt 2):200-9; discussion, 209-11. doi: 10.1016/0002-9394(55)91856-0. [DOI] [PubMed] [Google Scholar]
  14. Laibson P. R. Adenoviral keratoconjunctivitis. Int Ophthalmol Clin. 1975 Winter;15(4):187–201. doi: 10.1097/00004397-197501540-00016. [DOI] [PubMed] [Google Scholar]
  15. Laibson P. R., Dhiri S., Oconer J., Ortolan G. Corneal infiltrates in epidemic keratoconjunctivitis. Response to double-blind corticosteroid therapy. Arch Ophthalmol. 1970 Jul;84(1):36–40. doi: 10.1001/archopht.1970.00990040038010. [DOI] [PubMed] [Google Scholar]
  16. O'Day D. M., Guyer B., Hierholzer J. C. Clinical and laboratory evaluation of epidemic keratoconjunctivitis due to adenovirus types 8 and 19. Am J Ophthalmol. 1976 Feb;81(2):207–215. doi: 10.1016/0002-9394(76)90732-7. [DOI] [PubMed] [Google Scholar]
  18. Pereira H. G. Persistent infection by adenoviruses. J Clin Pathol Suppl (R Coll Pathol) 1972;6:39–42. [PMC free article] [PubMed] [Google Scholar]
  19. ROSEN L. A hemagglutination-inhibition technique for typing adenoviruses. Am J Hyg. 1960 Jan;71:120–128. doi: 10.1093/oxfordjournals.aje.a120085. [DOI] [PubMed] [Google Scholar]
  20. Sompolinsky D., Richmond S. Growth of Chlamydia trachomatis in McCoy cells treated with cytochalasin B. Appl Microbiol. 1974 Dec;28(6):912–914. doi: 10.1128/am.28.6.912-914.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Swyers J. S., Lausch R. N., Kaufman H. E. Corneal hypersensitivity to herpes simplex. Br J Ophthalmol. 1967 Dec;51(12):843–846. doi: 10.1136/bjo.51.12.843. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. THYGESON P. Office and dispensary transmissions of epidemic keratoconjunctivitis. Am J Ophthalmol. 1957 Apr;43(4 Pt 2):98–101. doi: 10.1016/0002-9394(57)91487-3. [DOI] [PubMed] [Google Scholar]
  23. Tullo A. B., Higgins P. G. Epidemic adenovirus keratoconjunctivitis. Lancet. 1978 Feb 25;1(8061):442–443. doi: 10.1016/s0140-6736(78)91229-1. [DOI] [PubMed] [Google Scholar]
  24. Zografos L. La kérato-conjonctivite de l'adéno-virus type 10. Ophthalmologica. 1977;174(2):61–64. doi: 10.1159/000308579. [DOI] [PubMed] [Google Scholar]

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