Skip to main content
PMC home page
Journal of Medical Genetics logoLink to Journal of Medical Genetics
. 1998 May;35(5):417–419. doi: 10.1136/jmg.35.5.417

Autosomal dominant juvenile recurrent parotitis.

E Reid 1, F Douglas 1, Y Crow 1, A Hollman 1, J Gibson 1
PMCID: PMC1051318  PMID: 9610807

Abstract

Juvenile recurrent parotitis is a common cause of inflammatory salivary gland swelling in children. A variety of aetiological factors has been proposed for the condition. Here we present a family where four members had juvenile recurrent parotitis and where two other family members may have had an atypical form of the condition. The segregation pattern in the family is consistent with autosomal dominant inheritance with incomplete penetrance and this suggests that, at least in some cases, genetic factors may be implicated in juvenile recurrent parotitis.

Full text

PDF
419

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Akaboshi I., Katsuki T., Jamamoto J., Matsuda I. Unique pattern of Epstein-Barr virus specific antibodies in recurrent parotitis. Lancet. 1983 Nov 5;2(8358):1049–1051. doi: 10.1016/s0140-6736(83)91038-3. [DOI] [PubMed] [Google Scholar]
  2. Bowling D. M., Ferry G., Rauch S. D., Goodman M. L. Intraductal tetracycline therapy for the treatment of chronic recurrent parotitis. Ear Nose Throat J. 1994 Apr;73(4):262–274. [PubMed] [Google Scholar]
  3. Cohen H. A., Gross S., Nussinovitch M., Frydman M., Varsano I. Recurrent parotitis. Arch Dis Child. 1992 Aug;67(8):1036–1037. doi: 10.1136/adc.67.8.1036. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Friis B., Karup Pedersen F., Schiødt M., Wiik A., Høj L., Andersen V. Immunological studies in two children with recurrent parotitis. Acta Paediatr Scand. 1983 Mar;72(2):265–268. doi: 10.1111/j.1651-2227.1983.tb09709.x. [DOI] [PubMed] [Google Scholar]
  5. Galili D., Marmary Y. Juvenile recurrent parotitis: clinicoradiologic follow-up study and the beneficial effect of sialography. Oral Surg Oral Med Oral Pathol. 1986 Jun;61(6):550–556. doi: 10.1016/0030-4220(86)90091-5. [DOI] [PubMed] [Google Scholar]
  6. Hara T., Nagata M., Mizuno Y., Ura Y., Matsuo M., Ueda K. Recurrent parotid swelling in children: clinical features useful for differential diagnosis of Sjögren's syndrome. Acta Paediatr. 1992 Jun-Jul;81(6-7):547–549. doi: 10.1111/j.1651-2227.1992.tb12292.x. [DOI] [PubMed] [Google Scholar]
  7. Hearth-Holmes M., Baethge B. A., Abreo F., Wolf R. E. Autoimmune exocrinopathy presenting as recurrent parotitis of childhood. Arch Otolaryngol Head Neck Surg. 1993 Mar;119(3):347–349. doi: 10.1001/archotol.1993.01880150103015. [DOI] [PubMed] [Google Scholar]
  8. JONES H. E. Recurrent parotitis in children. Arch Dis Child. 1953 Jun;28(139):182–186. doi: 10.1136/adc.28.139.182. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Nozaki H., Harasawa A., Hara H., Kohno A., Shigeta A. Ultrasonographic features of recurrent parotitis in childhood. Pediatr Radiol. 1994;24(2):98–100. doi: 10.1007/BF02020162. [DOI] [PubMed] [Google Scholar]
  10. SMITH M. Familial incidence of sialectasis. Br Med J. 1953 Dec 19;2(4850):1359–1359. doi: 10.1136/bmj.2.4850.1359. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Whitcomb D. C., Gorry M. C., Preston R. A., Furey W., Sossenheimer M. J., Ulrich C. D., Martin S. P., Gates L. K., Jr, Amann S. T., Toskes P. P. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet. 1996 Oct;14(2):141–145. doi: 10.1038/ng1096-141. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Medical Genetics are provided here courtesy of BMJ Publishing Group

RESOURCES