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. 1958 Aug;37(8):1131–1143. doi: 10.1172/JCI103703

Salicylates and Thyroid Function. I. Depression of Thyroid Function

Frank K Austen 1,2, Milton E Rubini 1,2, William H Meroney 1,2, J Wolff 1,2
PMCID: PMC1062780  PMID: 13563643

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ALEXANDER W. D., JOHNSON K. W. A comparison of the effects of acetylsalicyclic acid and DL-triiodothyronine in patients with myxoedema. Clin Sci. 1956 Nov;15(4):593–601. [PubMed] [Google Scholar]
  2. ALEXANDER W. D., JOHNSON K. W. Comparison of the metabolic stimulating action of aspirin and thyroid. Nature. 1956 Aug 4;178(4527):259–260. doi: 10.1038/178259a0. [DOI] [PubMed] [Google Scholar]
  3. BARKER S. B., HUMPHREY M. J., SOLEY M. H. The clinical determination of protein-bound iodine. J Clin Invest. 1951 Jan;30(1):55–62. doi: 10.1172/JCI102416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BERSON S. A., YALOW R. S., SORRENTINO J., ROSWIT B. The determination of thyroidal and renal plasma I131 clearance rates as a routine diagnostic test of thyroid dysfunction. J Clin Invest. 1952 Feb;31(2):141–158. doi: 10.1172/JCI102585. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. BRICKER N. S., HLAD C. J., Jr Observations on the mechanism of the renal clearance of I131. J Clin Invest. 1955 Jul;34(7 Pt 1):1057–1072. doi: 10.1172/JCI103155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. BRODY T. M. Action of sodium salicylate and related compounds on tissue metabolism in vitro. J Pharmacol Exp Ther. 1956 May;117(1):39–51. [PubMed] [Google Scholar]
  7. CASTOR C. W., BEIERWALTES W. Effect of 2, 4-dinitrophenol on thyroid function in man. J Clin Endocrinol Metab. 1956 Aug;16(8):1026–1031. doi: 10.1210/jcem-16-8-1026. [DOI] [PubMed] [Google Scholar]
  8. COCHRAN J. B. Further observations on the metabolic stimulating effect of salicylate. Br Med J. 1954 Mar 27;1(4864):733–734. doi: 10.1136/bmj.1.4864.733. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. COCHRAN J. B. The respiratory effects of salicylate. Br Med J. 1952 Nov 1;2(4791):964–967. doi: 10.1136/bmj.2.4791.964. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Cutting W. C., Rytand D. A., Tainter M. L. RELATIONSHIP BETWEEN BLOOD CHOLESTEROL AND INCREASED METABOLISM FROM DINITROPHENOL AND THYROID. J Clin Invest. 1934 Jul;13(4):547–552. doi: 10.1172/JCI100604. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. GOLDBERG R. C., GREEP R. O., WOLFF J. Studies on the nature of the thyroid-pituitary interrelationship. Endocrinology. 1957 Jan;60(1):38–52. doi: 10.1210/endo-60-1-38. [DOI] [PubMed] [Google Scholar]
  12. GOLDBERG R. C., WOLFF J., GREEP R. O. The mechanism of depression of plasma protein bound iodine by 2,4 dinitrophenol. Endocrinology. 1955 May;56(5):560–566. doi: 10.1210/endo-56-5-560. [DOI] [PubMed] [Google Scholar]
  13. INGBAR S. H., FREINKEL N. Simultaneous estimation of rates of thyroxine degradation and thyroid hormone synthesis. J Clin Invest. 1955 Jun;34(6):808–819. doi: 10.1172/JCI103136. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Keating F. R., Wang J. C., Luellen T. J., Williams M. M., Power M. H., McConahey W. M. THE MEASUREMENT OF THE IODINE-ACCUMULATING FUNCTION OF THE HUMAN THYROID GLAND. J Clin Invest. 1949 Mar;28(2):217–227. doi: 10.1172/JCI102063. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. LARDY H. A., WELLMAN H. Oxidative phosphorylations; rôle of inorganic phosphate and acceptor systems in control of metabolic rates. J Biol Chem. 1952 Mar;195(1):215–224. [PubMed] [Google Scholar]
  16. MEADE B. W. Effect of certain hydroxybenzoic acids on the oxygen consumption of Wistar rats. Ann Rheum Dis. 1954 Mar;13(1):60–62. doi: 10.1136/ard.13.1.60. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. MECKSTROTH C. V., RAPPORT R. L., CURTIS G. M., SIMCOX S. J. The laboratory diagnosis of extrathyroidal hypermetabolism. J Clin Endocrinol Metab. 1952 Oct;12(10):1373–1379. doi: 10.1210/jcem-12-10-1373. [DOI] [PubMed] [Google Scholar]
  18. PACKER L. Coupled phosphorylation in rat heart muscle sarcosomes. Arch Biochem Biophys. 1957 Jul;70(1):290–293. doi: 10.1016/0003-9861(57)90105-4. [DOI] [PubMed] [Google Scholar]
  19. REID J. A new outlook on the action of salicylate. Scott Med J. 1957 Mar;2(3):91–96. doi: 10.1177/003693305700200303. [DOI] [PubMed] [Google Scholar]
  20. ROBBINS J., RALL J. E. The interaction of thyroid hormones and protein in biological fluids. Recent Prog Horm Res. 1957;13:161–208. [PubMed] [Google Scholar]
  21. ROBBINS J. Reverse-flow zone electrophoresis; a method for determining the thyroxine-binding capacity of serum protein. Arch Biochem Biophys. 1956 Aug;63(2):461–469. doi: 10.1016/0003-9861(56)90062-5. [DOI] [PubMed] [Google Scholar]
  22. SEEBERG V. P., HANSEN D., WHITNEY B. Absorption and distribution of salicylamide. J Pharmacol Exp Ther. 1951 Mar;101(3):275–282. [PubMed] [Google Scholar]
  23. SMITH M. J. H., MEADE B. W. The effect of salicylate on glycosuria, blood glucose and liver glycogen of the alloxan-diabetic rat. Biochem J. 1952 Apr;51(1):18–20. doi: 10.1042/bj0510018. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. SMITH M. J., JEFFREY S. W. The effects of salicylate on oxygen consumption and carbohydrate metabolism in the isolated rat diaphragm. Biochem J. 1956 Jul;63(3):524–528. doi: 10.1042/bj0630524. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. SPROULL D. H. A peripheral action of sodium salicylate. Br J Pharmacol Chemother. 1954 Sep;9(3):262–264. doi: 10.1111/j.1476-5381.1954.tb01678.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. STERLING K., CHODOS R. B. Radiothyroxine turnover studies in myxedema, thyrotoxicosis, and hypermetabolism without endocrine disease. J Clin Invest. 1956 Jul;35(7):806–813. doi: 10.1172/JCI103333. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. STERLING K., LASHOF J. C., MAN E. B. Disappearance from serum of I131-labeled l-thyroxine and l-triiodothyronine in euthyroid subjects. J Clin Invest. 1954 Jul;33(7):1031–1035. doi: 10.1172/JCI102970. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. TENNEY S. M., MILLER R. M. The respiratory and circulatory actions of salicylate. Am J Med. 1955 Oct;19(4):498–508. doi: 10.1016/0002-9343(55)90342-9. [DOI] [PubMed] [Google Scholar]
  29. WOLFF J., AUSTEN F. K. Salicylates and thyroid function. II. The effect on the thyroid-pituitary interrelation. J Clin Invest. 1958 Aug;37(8):1144–1152. doi: 10.1172/JCI103704. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. WOLFF J., RUBIN L., CHAIKOFF I. L. The influence of 2,4-dinitrophenol on plasma protein bound iodine. J Pharmacol Exp Ther. 1950 Jan;98(1):45–48. [PubMed] [Google Scholar]

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