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Journal of Clinical Pathology logoLink to Journal of Clinical Pathology
. 1980 Mar;33(3):282–287. doi: 10.1136/jcp.33.3.282

Prevalence and intraoral distribution of Candida albicans in Sjögren's syndrome.

L Tapper-Jones, M Aldred, D M Walker
PMCID: PMC1146053  PMID: 6991530

Abstract

An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at almost all sites in the Sjögren's patients than in the controls. The distribution of candida was also altered, being significantly higher in the floor of the mouth and anterior labial sulcus in the Sjögren's group. There was an approximate inverse relationship between candida populations and rate of salivary flow. Mean candida densities were found to be significantly higher in those Sjögren's patients with detectable serum rheumatoid factor in the serum. However, patients with primary Sjögren's syndrome had significantly higher mean candida densities compared with patients with secondary Sjögren's syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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