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. 1980 Mar;33(3):282–287. doi: 10.1136/jcp.33.3.282

Prevalence and intraoral distribution of Candida albicans in Sjögren's syndrome.

L Tapper-Jones, M Aldred, D M Walker
PMCID: PMC1146053  PMID: 6991530

Abstract

An imprint culture technique has been employed to study the prevalence and intraoral distribution of Candida albicans in 16 patients with Sjögren's syndrome and in 16 healthy controls matched for age, sex, and dental status. The prevalence and intraoral density of C. albicans was found to be significantly higher at almost all sites in the Sjögren's patients than in the controls. The distribution of candida was also altered, being significantly higher in the floor of the mouth and anterior labial sulcus in the Sjögren's group. There was an approximate inverse relationship between candida populations and rate of salivary flow. Mean candida densities were found to be significantly higher in those Sjögren's patients with detectable serum rheumatoid factor in the serum. However, patients with primary Sjögren's syndrome had significantly higher mean candida densities compared with patients with secondary Sjögren's syndrome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arendorf T. M., Walker D. M. Oral candidal populations in health and disease. Br Dent J. 1979 Nov 20;147(10):267–272. doi: 10.1038/sj.bdj.4804344. [DOI] [PubMed] [Google Scholar]
  2. BARTELS H. A., BLECHMAN H. Survey of the yeast populations in saliva and an evaluation of some procedures for identification of Candida albicans. J Dent Res. 1962 Nov-Dec;41:1386–1390. doi: 10.1177/00220345620410061701. [DOI] [PubMed] [Google Scholar]
  3. BLOCH K. J., BUCHANAN W. W., WOHL M. J., BUNIM J. J. SJOEGREN'S SYNDROME. A CLINICAL, PATHOLOGICAL, AND SEROLOGICAL STUDY OF SIXTY-TWO CASES. Medicine (Baltimore) 1965 May;44:187–231. [PubMed] [Google Scholar]
  4. Challacombe S. J., Barkhan P., Lehner T. Haematological features and differentiation of recurrent oral ulceration. Br J Oral Surg. 1977 Jul;15(1):37–48. doi: 10.1016/0007-117x(77)90006-3. [DOI] [PubMed] [Google Scholar]
  5. Chisholm D. M., Mason D. K. Salivary gland function in Sjögren's syndrome: a review. Br Dent J. 1973 Nov 6;135(9):393–399. doi: 10.1038/sj.bdj.4803096. [DOI] [PubMed] [Google Scholar]
  6. Dolan C. T. A practical approach to identification of yeast-like organisms. Am J Clin Pathol. 1971 May;55(5):580–590. doi: 10.1093/ajcp/55.5.580. [DOI] [PubMed] [Google Scholar]
  7. KRASNER R. I., YOUNG G., YUDKOFSKY P. L. Interactions of oral strains of Candida albicans and lactobacilli. J Bacteriol. 1956 Oct;72(4):525–529. doi: 10.1128/jb.72.4.525-529.1956. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Lehner T. Immunofluorescence study of Candida albicans in candidiasis, carriers and controls. J Pathol Bacteriol. 1966 Jan;91(1):97–104. doi: 10.1002/path.1700910114. [DOI] [PubMed] [Google Scholar]
  9. MacFarlane T. W., Mason D. K. Changes in the oral flora in Sjögren's syndrome. J Clin Pathol. 1974 May;27(5):416–419. doi: 10.1136/jcp.27.5.416. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Williams R. C., Gibbons R. J. Inhibition of bacterial adherence by secretory immunoglobulin A: a mechanism of antigen disposal. Science. 1972 Aug 25;177(4050):697–699. doi: 10.1126/science.177.4050.697. [DOI] [PubMed] [Google Scholar]
  11. Williamson J. J. A study of extent of variation in daily counts of Candida albicans in saliva. Aust Dent J. 1972 Apr;17(2):106–109. doi: 10.1111/j.1834-7819.1972.tb02762.x. [DOI] [PubMed] [Google Scholar]

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