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. 1984 Feb 1;217(3):813–817. doi: 10.1042/bj2170813

Cystatin. Amino acid sequence and possible secondary structure.

C Schwabe, A Anastasi, H Crow, J K McDonald, A J Barrett
PMCID: PMC1153285  PMID: 6712597

Abstract

The amino acid sequence of cystatin, the protein from chicken egg-white that is a tight-binding inhibitor of many cysteine proteinases, is reported. Cystatin is composed of 116 amino acid residues, and the Mr is calculated to be 13 143. No striking similarity to any other known sequence has been detected. The results of computer analysis of the sequence and c.d. spectrometry indicate that the secondary structure includes relatively little alpha-helix (about 20%) and that the remainder is mainly beta-structure.

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Selected References

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