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. 1982 May 15;204(2):609–612. doi: 10.1042/bj2040609

The apoprotein B-independent hepatic uptake of chylomicron remnants.

J Borensztajn, G S Getz, R J Padley, T J Kotlar
PMCID: PMC1158391  PMID: 7115352

Abstract

Rat lymph chylomicrons were treated with Pronase resulting in particles completely devoid of surface apoproteins. On re-incubation with serum, the Pronase-treated chylomicrons re-acquired, by transfer from other lipoproteins, all apoproteins except apoprotein B, which is water-insoluble and non-transferable. When two groups of rats were injected with [3H]cholesterol-labelled control or Pronase-treated chylomicrons, radioactivity was incorporated into the liver of both groups at similar rates. It is concluded that the remnants of the control and Pronase-treated chylomicrons formed in the vascular space were recognized and taken up by liver cells by a process that does not require apoprotein B.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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