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. 2001 Sep;109(9):881–891. doi: 10.1289/ehp.01109881

Progress in the application of DNA microarrays.

E K Lobenhofer 1, P R Bushel 1, C A Afshari 1, H K Hamadeh 1
PMCID: PMC1240437  PMID: 11673116

Abstract

Microarray technology has been applied to a variety of different fields to address fundamental research questions. The use of microarrays, or DNA chips, to study the gene expression profiles of biologic samples began in 1995. Since that time, the fundamental concepts behind the chip, the technology required for making and using these chips, and the multitude of statistical tools for analyzing the data have been extensively reviewed. For this reason, the focus of this review will be not on the technology itself but on the application of microarrays as a research tool and the future challenges of the field.

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Selected References

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