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. 1987 Jun 20;294(6587):1573–1576. doi: 10.1136/bmj.294.6587.1573

Reduction in postprandial energy expenditure during pregnancy.

P J Illingworth, R T Jung, P W Howie, T E Isles
PMCID: PMC1246726  PMID: 3113536

Abstract

Energy expenditure was measured during pregnancy in seven primigravid women at 12-15, 25-28, and 34-36 weeks and after the cessation of lactation. On each occasion the resting metabolic rate and the increase in metabolic rate after ingestion of a liquid test meal were measured by indirect calorimetry. In absolute terms the resting metabolic rate increased steadily during pregnancy but when expressed per unit of body weight no change was found. The energetic response to a mixed constituent meal was significantly reduced by 28% in the middle trimester of pregnancy. These findings suggest a possible maternal adaptation to increase energetic efficiency at a time when the energy demands of the fetus are high.

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Selected References

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  1. BLEICHER S. J., O'SULLIVAN J. B., FREINKEL N. CARBOHYDRATE METABOLISM IN PREGNANCY. V. THE INTERRELATIONS OF GLUCOSE, INSULIN AND FREE FATTY ACIDS IN LATE PREGNANCY AND POST PARTUM. N Engl J Med. 1964 Oct 22;271:866–872. doi: 10.1056/NEJM196410222711702. [DOI] [PubMed] [Google Scholar]
  2. Banerjee B., Khew K. S., Saha N. A comparative study of energy expenditure in some common daily activities of non-pregnant and pregnant Chinese, Malay and Indian women. J Obstet Gynaecol Br Commonw. 1971 Feb;78(2):113–116. doi: 10.1111/j.1471-0528.1971.tb00243.x. [DOI] [PubMed] [Google Scholar]
  3. Blackburn M. W., Calloway D. H. Energy expenditure and consumption of mature, pregnant and lactating women. J Am Diet Assoc. 1976 Jul;69(1):29–37. [PubMed] [Google Scholar]
  4. Durnin J. V., McKillop F. M., Grant S., Fitzgerald G. Is nutritional status endangered by virtually no extra intake during pregnancy? Lancet. 1985 Oct 12;2(8459):823–825. doi: 10.1016/s0140-6736(85)90806-2. [DOI] [PubMed] [Google Scholar]
  5. Felig P. Insulin is the mediator of feeding-related thermogenesis: insulin resistance and/or deficiency results in a thermogenic defect which contributes to the pathogenesis of obesity. Clin Physiol. 1984 Aug;4(4):267–273. doi: 10.1111/j.1475-097x.1984.tb00802.x. [DOI] [PubMed] [Google Scholar]
  6. Hervey G. R., Tobin G. Luxuskonsumption, diet-induced thermogenesis and brown fat: a critical review. Clin Sci (Lond) 1983 Jan;64(1):7–18. doi: 10.1042/cs0640007. [DOI] [PubMed] [Google Scholar]
  7. Illingworth P. J., Jung R. T., Howie P. W., Leslie P., Isles T. E. Diminution in energy expenditure during lactation. Br Med J (Clin Res Ed) 1986 Feb 15;292(6518):437–441. doi: 10.1136/bmj.292.6518.437. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Jimenez M. H., Newton N. Activity and work during pregnancy and the postpartum period: a cross-cultural study of 202 societies. Am J Obstet Gynecol. 1979 Sep 15;135(2):171–176. doi: 10.1016/0002-9378(79)90337-5. [DOI] [PubMed] [Google Scholar]
  9. Kaplan M. L., Leveille G. A. Calorigenic response in obese and nonobese women. Am J Clin Nutr. 1976 Oct;29(10):1108–1113. doi: 10.1093/ajcn/29.10.1108. [DOI] [PubMed] [Google Scholar]
  10. Knuttgen H. G., Emerson K., Jr Physiological response to pregnancy at rest and during exercise. J Appl Physiol. 1974 May;36(5):549–553. doi: 10.1152/jappl.1974.36.5.549. [DOI] [PubMed] [Google Scholar]
  11. Lawrence M., Lawrence F., Lamb W. H., Whitehead R. G. Maintenance energy cost of pregnancy in rural Gambian women and influence of dietary status. Lancet. 1984 Aug 18;2(8399):363–365. doi: 10.1016/s0140-6736(84)90538-5. [DOI] [PubMed] [Google Scholar]
  12. Macdonald I. A., Bennett T., Fellows I. W. Catecholamines and the control of metabolism in man. Clin Sci (Lond) 1985 Jun;68(6):613–619. doi: 10.1042/cs0680613. [DOI] [PubMed] [Google Scholar]
  13. McNeill G., Payne P. R. Energy expenditure of pregnant and lactating women. Lancet. 1985 Nov 30;2(8466):1237–1238. doi: 10.1016/s0140-6736(85)90760-3. [DOI] [PubMed] [Google Scholar]
  14. Nagy L. E., King J. C. Energy expenditure of pregnant women at rest or walking self-paced. Am J Clin Nutr. 1983 Sep;38(3):369–376. doi: 10.1093/ajcn/38.3.369. [DOI] [PubMed] [Google Scholar]
  15. Pernoll M. L., Metcalfe J., Schlenker T. L., Welch J. E., Matsumoto J. A. Oxygen consumption at rest and during exercise in pregnancy. Respir Physiol. 1975 Dec;25(3):285–293. doi: 10.1016/0034-5687(75)90004-3. [DOI] [PubMed] [Google Scholar]
  16. Pittet P., Chappuis P., Acheson K., De Techtermann F., Jéquier E. Thermic effect of glucose in obese subjects studied by direct and indirect calorimetry. Br J Nutr. 1976 Mar;35(2):281–292. doi: 10.1079/bjn19760033. [DOI] [PubMed] [Google Scholar]
  17. Ravussin E., Bogardus C., Schwartz R. S., Robbins D. C., Wolfe R. R., Horton E. S., Danforth E., Jr, Sims E. A. Thermic effect of infused glucose and insulin in man. Decreased response with increased insulin resistance in obesity and noninsulin-dependent diabetes mellitus. J Clin Invest. 1983 Sep;72(3):893–902. doi: 10.1172/JCI111060. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Rothwell N. J., Stock M. J. Luxuskonsumption, diet-induced thermogenesis and brown fat: the case in favour. Clin Sci (Lond) 1983 Jan;64(1):19–23. doi: 10.1042/cs0640019. [DOI] [PubMed] [Google Scholar]
  19. Schwartz R. S., Ravussin E., Massari M., O'Connell M., Robbins D. C. The thermic effect of carbohydrate versus fat feeding in man. Metabolism. 1985 Mar;34(3):285–293. doi: 10.1016/0026-0495(85)90014-9. [DOI] [PubMed] [Google Scholar]
  20. Seitchik J. Body composition and energy expenditure during rest and work in pregnancy. Am J Obstet Gynecol. 1967 Mar 1;97(5):701–713. doi: 10.1016/0002-9378(67)90455-3. [DOI] [PubMed] [Google Scholar]
  21. Shetty P. S., Jung R. T., James W. P., Barrand M. A., Callingham B. A. Postprandial thermogenesis in obesity. Clin Sci (Lond) 1981 May;60(5):519–525. doi: 10.1042/cs0600519. [DOI] [PubMed] [Google Scholar]
  22. Trinder P. Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen. J Clin Pathol. 1969 Mar;22(2):158–161. doi: 10.1136/jcp.22.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. WEIR J. B. DE B. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol. 1949 Aug;109(1-2):1–9. doi: 10.1113/jphysiol.1949.sp004363. [DOI] [PMC free article] [PubMed] [Google Scholar]

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