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. 1966 Mar;98(3):754–762. doi: 10.1042/bj0980754

The choline acetyltransferase of human placenta

D Morris 1
PMCID: PMC1264916  PMID: 5911523

Abstract

1. Various methods for the extraction of choline acetyltransferase (acetyl-CoA–choline O-acetyltransferase, EC 2.3.1.6) from immature human placenta (18–28 weeks of gestation) are described. 2. The crude enzyme was found to be stable at −18° and +4° under a variety of conditions. 3. Purification methods, including ammonium sulphate fractionation, gel filtration on various grades of Sephadex and DEAE-Sephadex fractionation, have yielded a preparation of high specific activity.

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Selected References

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