Skip to main content
PMC home page
Gut logoLink to Gut
. 1990 Mar;31(3):270–273. doi: 10.1136/gut.31.3.270

Arterial oxygen saturation during upper gastrointestinal endoscopy: the effects of a midazolam/pethidine combination.

A W Murray 1, C G Morran 1, G N Kenny 1, J R Anderson 1
PMCID: PMC1378264  PMID: 2323587

Abstract

This study was performed to assess the severity and duration of hypoxia during and after prolonged upper gastrointestinal endoscopy. Twenty patients were studied using a non-invasive pulse oximeter. Significant reductions in oxygen saturation were noted during endoscopy and remained below the preexamination level during the one hour period after the examination. This study indicates that pulse oximetry is a useful monitor for detection of hypoxia during and after endoscopy.

Full text

PDF
270

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bell G. D., Bown S., Morden A., Coady T., Logan R. F. Prevention of hypoxaemia during upper-gastrointestinal endoscopy by means of oxygen via nasal cannulae. Lancet. 1987 May 2;1(8540):1022–1024. doi: 10.1016/s0140-6736(87)92282-3. [DOI] [PubMed] [Google Scholar]
  2. Bell G. D., Morden A., Coady T., Lee J., Logan R. F. A comparison of diazepam and midazolam as endoscopy premedication assessing changes in ventilation and oxygen saturation. Br J Clin Pharmacol. 1988 Nov;26(5):595–600. doi: 10.1111/j.1365-2125.1988.tb05300.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Bell G. D., Reeve P. A., Moshiri M., Morden A., Coady T., Stapleton P. J., Logan R. F. Intravenous midazolam: a study of the degree of oxygen desaturation occurring during upper gastrointestinal endoscopy. Br J Clin Pharmacol. 1987 Jun;23(6):703–708. doi: 10.1111/j.1365-2125.1987.tb03104.x. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Lavies N. G., Creasy T., Harris K., Hanning C. D. Arterial oxygen saturation during upper gastrointestinal endoscopy: influence of sedation and operator experience. Am J Gastroenterol. 1988 Jun;83(6):618–622. [PubMed] [Google Scholar]
  5. Mihm F. G., Halperin B. D. Noninvasive detection of profound arterial desaturations using a pulse oximetry device. Anesthesiology. 1985 Jan;62(1):85–87. doi: 10.1097/00000542-198501000-00020. [DOI] [PubMed] [Google Scholar]
  6. Neil S. G., Lam A. M., Turnbull K. W., Tremper K. K. A panel summary: Monitoring of oxygen. Can J Anaesth. 1987 Jan;34(1):56–63. doi: 10.1007/BF03007683. [DOI] [PubMed] [Google Scholar]
  7. Pecora A. A., Chiesa J. C., Alloy A. M., Santoro J., Lazarus B. The effect of upper gastrointestinal endoscopy on arterial O2 tension in smokers and nonsmokers with and without premedication. Gastrointest Endosc. 1984 Oct;30(5):284–288. doi: 10.1016/s0016-5107(84)72419-9. [DOI] [PubMed] [Google Scholar]
  8. Rostykus P. S., McDonald G. B., Albert R. K. Upper intestinal endoscopy induces hypoxemia in patients with obstructive pulmonary disease. Gastroenterology. 1980 Mar;78(3):488–491. [PubMed] [Google Scholar]
  9. Rozen P., Fireman Z., Gilat T. Arterial oxygen tension changes in elderly patients undergoing upper gastrointestinal endoscopy. II. Influence of the narcotic premedication and endoscope diameter. Scand J Gastroenterol. 1981;16(2):299–303. doi: 10.3109/00365528109181972. [DOI] [PubMed] [Google Scholar]
  10. Rozen P., Fireman Z., Gilat T. The causes of hypoxemia in elderly patients during endoscopy. Gastrointest Endosc. 1982 Nov;28(4):243–246. doi: 10.1016/s0016-5107(82)73101-3. [DOI] [PubMed] [Google Scholar]
  11. Whorwell P. J., Smith C. L., Foster K. J. Arterial blood gas tensions during upper gastrointestinal endoscopy. Gut. 1976 Oct;17(10):797–800. doi: 10.1136/gut.17.10.797. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Zsigmond E. K., Flynn K., Martinez O. A. Diazepam and meperidine on arterial blood gases in healthy volunteers. J Clin Pharmacol. 1974 Jul;14(7):377–381. doi: 10.1002/j.1552-4604.1974.tb01414.x. [DOI] [PubMed] [Google Scholar]
  13. Zsigmond E. K., Shively J. G., Flynn K. Diazepam and meperidine on arterial blood gases in patients with chronic obstructive pulmonary disease. J Clin Pharmacol. 1975 May-Jun;15(5-6):464–469. doi: 10.1002/j.1552-4604.1975.tb02370.x. [DOI] [PubMed] [Google Scholar]

Articles from Gut are provided here courtesy of BMJ Publishing Group

RESOURCES