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. 1992 Aug;76(4):668–670.

Lymphocytes bearing the gamma delta T-cell receptor in acute toxoplasmosis.

F Scalise 1, R Gerli 1, G Castellucci 1, F Spinozzi 1, G M Fabietti 1, S Crupi 1, L Sensi 1, R Britta 1, R Vaccaro 1, A Bertotto 1
PMCID: PMC1421574  PMID: 1398756

Abstract

Although the relative and absolute numbers of CD3+ cells (T lymphocytes) were similar in eight children with acquired Toxoplasma gondii infection and 10 uninfected age- and sex-matched healthy controls, the proportion of cells bearing the gamma delta T-cell receptor was significantly higher in the subjects with acute toxoplasmosis. The great majority of gamma delta T cells from the infected patients expressed covalently bound gamma delta chains on their surface, i.e. were BB3+ lymphocytes. Since the gamma delta T-cell subsets exert both restricted and unrestricted major histocompatibility complex cytotoxicity, further research is needed to elucidate the role of gamma delta T cells in the control of this coccidian protozoan infection.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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