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. 1984 Jul;52(3):389–394.

Role of maternal immunity in the protection of newborn ferrets against infection with a virulent influenza virus.

R H Husseini, C Sweet, H Overton, H Smith
PMCID: PMC1454495  PMID: 6745992

Abstract

Intranasal infection of newborn ferrets with a virulent strain of influenza virus invariably resulted in their deaths following virus replication to high titre in both lung and nasal turbinates (Collie et al., 1980). However, a similar challenge of newborn ferrets born to mothers immunized by infection with virulent or attenuated viruses resulted in complete protection; no virus replicated in their lungs and little or no virus was isolated from their nasal turbinates. Protection appeared to be antibody-mediated since it was sub-type-specific and milk-derived since newborn ferrets born to non-immune mothers but fostered onto immune mothers exhibited a similar level of protection to neonates born to and suckled by immune mothers.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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