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. 1978 Dec;53(12):961–963. doi: 10.1136/adc.53.12.961

Depigmented hair. The earliest sign of tuberous sclerosis.

R C McWilliam, J B Stephenson
PMCID: PMC1545179  PMID: 747403

Abstract

We have studied 4 children with tuberous sclerosis with one or more patches of depigmented scalp hair and in each case these were noticed by the parents at birth. In one patient the finding of a tuft of white hair preceded the appearance of white macules by many months. A tuft of white scalp hair is a useful new sign of tuberous sclerosis in the newborn and young child, and the hair should be examined as carefully as the skin when early 'organic' seizures are unexplained.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fitzpatrick T. B., Szabó G., Hori Y., Simone A. A., Reed W. B., Greenberg M. H. White leaf-shaped macules. Earliest visible sign of tuberous sclerosis. Arch Dermatol. 1968 Jul;98(1):1–6. [PubMed] [Google Scholar]
  2. Fois A., Pindinelli C. A., Berardi R. Early signs of tuberous sclerosis in infancy and childhood. Helv Paediatr Acta. 1973 Oct;28(4):313–321. [PubMed] [Google Scholar]
  3. GOLD A. P., FREEMAN J. M. DEPIGMENTED NEVI: THE EARLIEST SIGN OF TUBEROUS SCLEROSIS. Pediatrics. 1965 Jun;35:1003–1005. [PubMed] [Google Scholar]
  4. NICKEL W. R., REED W. B. Tuberous sclerosis. Special reference to the microscopic alterations in the cutaneous hamartomas. Arch Dermatol. 1962 Feb;85:209–226. doi: 10.1001/archderm.1962.01590020049006. [DOI] [PubMed] [Google Scholar]
  5. Pampiglione G., Moynahan E. J. The tuberous sclerosis syndrome: clinical and EEG studies in 100 children. J Neurol Neurosurg Psychiatry. 1976 Jul;39(7):666–673. doi: 10.1136/jnnp.39.7.666. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Pampiglione G., Pugh E. Letter: Infantile spasms and subsequent appearance of tuberous sclerosis syndrome. Lancet. 1975 Nov 22;2(7943):1046–1046. doi: 10.1016/s0140-6736(75)90343-8. [DOI] [PubMed] [Google Scholar]

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