Abstract
87 of 90 consecutive cases of medulloblastoma diagnosed at The Hospital for Sick Children, London, in the 10-year period 1965-74 were followed-up until death or until 1 January 1978. Only one patient survived in the 1st 5-year period and is a cure. In the 2nd 5-year period 17 (41%) of 41 patients presenting are alive and, of these, 11 are 5-year survivors (=39% of possible 5-year survivors). Reasons for this improvement are discussed; it is thought likely that the main contribution is improved radiotherapeutic techniques.
Full text
PDF![200](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f1/1545229/6dcbe63440f9/archdisch00795-0034.png)
![201](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f1/1545229/82a63b437c33/archdisch00795-0035.png)
![202](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f1/1545229/fe7018769f4a/archdisch00795-0036.png)
![203](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/30f1/1545229/6ead7d9aa177/archdisch00795-0037.png)
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bloom H. J. Combined modality therapy for intracranial tumors. Cancer. 1975 Jan;35(1):111–120. doi: 10.1002/1097-0142(197501)35:1<111::aid-cncr2820350116>3.0.co;2-#. [DOI] [PubMed] [Google Scholar]
- Bloom H. J., Wallace E. N., Henk J. M. The treatment and prognosis of medulloblastoma in children. A study of 82 verified cases. Am J Roentgenol Radium Ther Nucl Med. 1969 Jan;105(1):43–62. doi: 10.2214/ajr.105.1.43. [DOI] [PubMed] [Google Scholar]
- Chatty E. M., Earle K. M. Medulloblastoma. A report of 201 cases with emphasis on the relationship of histologic variants to survival. Cancer. 1971 Oct;28(4):977–983. doi: 10.1002/1097-0142(1971)28:4<977::aid-cncr2820280422>3.0.co;2-7. [DOI] [PubMed] [Google Scholar]
- Gjerris F. Clinical aspects and long-term prognosis of intracranial tumours in infancy and childhood. Dev Med Child Neurol. 1976 Apr;18(2):145–159. doi: 10.1111/j.1469-8749.1976.tb03623.x. [DOI] [PubMed] [Google Scholar]
- Hope-Stone H. F. Results of treatment of medulloblastomas. J Neurosurg. 1970 Jan;32(1):83–88. doi: 10.3171/jns.1970.32.1.0083. [DOI] [PubMed] [Google Scholar]
- Makeever L. C., King J. D. Medulloblastoma with extracranial metastasis through a ventriculovenous shunt. Report of a case and review of the literature. Am J Clin Pathol. 1966 Aug;46(2):245–249. doi: 10.1093/ajcp/46.2.245. [DOI] [PubMed] [Google Scholar]
- McFarland D. R., Horwitz H., Saenger E. L., Bahr G. K. Medulloblastoma--a review of prognosis and survival. Br J Radiol. 1969 Mar;42(495):198–214. doi: 10.1259/0007-1285-42-495-198. [DOI] [PubMed] [Google Scholar]