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. 1986 Apr;38(4):428–436.

Sequences homologous to the human D1S1 locus present on human chromosome 3.

B Carritt, H M Welch, N J Parry-Jones
PMCID: PMC1684798  PMID: 3010709

Abstract

We have investigated the segregation, in somatic cell hybrids, of the human D1S1 locus, previously assigned to 1p36 by in situ hybridization. We have shown that the clone which defines this locus, lambda Ch4A-H3, originates from human chromosome 3, but contains a 1.7-kilobase (kb) PstI-HindIII repetitive element that is also present on chromosome 1, probably distal to PGD. The clone recognizes restriction fragment length polymorphisms within the single-copy sequence on chromosome 3 and one for the enzyme StuI in the repeated sequence on chromosome 1. These experiments thus expose a level of complexity in the D1S1 locus not revealed by earlier in situ hybridization studies.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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