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. 1973 Jan;47(1):59–68. doi: 10.1111/j.1476-5381.1973.tb08158.x

Renin-like activity of the rat submaxillary gland

Characterization and the effect of several drugs and stimuli

Y Gutman, M Levy, J Shorr
PMCID: PMC1776516  PMID: 4352088

Abstract

1. Renin-like activity was found in rat submaxillary glands.

2. This activity was destroyed by boiling, was non-dialyzable and showed an optimum at approximately 50° C.

3. Renin-like activity in the submaxillary gland was not diminished 24 h after nephrectomy but was considerably reduced after ligature of the submaxillary duct.

4. Renin-like activity in the submaxillary gland was reduced following food-deprivation, water-deprivation or hypovolemia.

5. Renin-like activity in the rat submaxillary gland was increased after isoproterenol administration but not following pilocarpine.

6. Renin-like activity in the rat submaxillary gland was increased considerably by administration of NaCl or KCl, as well as following adrenalectomy.

7. Chlorothiazide and ouabain increased submaxillary renin-like activity but diazoxide did not affect this activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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