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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1996 Sep;59(3):726–730.

A pseudolikelihood approach to correcting for ascertainment bias in family studies.

D Rabinowitz 1
PMCID: PMC1914909  PMID: 8751874

Abstract

The Cannings and Thompson approach to correcting for ascertainment bias in family studies is extended to settings with multiple ascertainment. The extension is based on maximizing a pseudolikelihood. Two approaches to computing standard errors for the maximum pseudolikelihood estimate are described. One is especially simple to compute, while the other is more generally applicable. Simulation experiments suggest that the standard-error computations can be quite accurate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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