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. 1994 Nov;176(22):7096–7101. doi: 10.1128/jb.176.22.7096-7101.1994

Molecular cloning and characterization of the aklavinone 11-hydroxylase gene of Streptomyces peucetius subsp. caesius ATCC 27952.

Y S Hong 1, C K Hwang 1, S K Hong 1, Y H Kim 1, J J Lee 1
PMCID: PMC197087  PMID: 7961477

Abstract

The gene encoding aklavinone 11-hydroxylase of Streptomyces peucetius subsp. caesius ATCC 27952 was cloned and sequenced. The deduced amino acid sequence of the gene contains at least two common motifs of well-conserved amino acid sequences of several flavin-type bacterial hydroxylases. The hydroxylase gene is apparently transcribed from a single transcriptional start point. The phenotype of a dnrF mutant generated by gene disruption supports the idea that the dnrF gene encodes aklavinone 11-hydroxylase.

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Selected References

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