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. 1979 Feb;39(2):116–121. doi: 10.1038/bjc.1979.21

Serological aspects of rat tumour xenograft growth in athymic nude mice.

M V Pimm, R W Baldwin
PMCID: PMC2009841  PMID: 373782

Abstract

The serum of athymic nude mice bearing rat tumour xenografts has been examined for tumour-specific antigen. With a sarcoma and a hepatoma, tumour-specific antigen expression continued in xenograft growths, and sera of tumour-bearing mice contained free antigen, assayed by its ability to neutralise reactivity of tumour-immune rat sera against tumour target cells in an indirect membrane-immunofluorescence test. In contrast, no anti-rat antibody was detectable in sera of mice bearing the xenografts, or rejecting cells injected in admixture with BCG.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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