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British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1984 Apr;65(2):267–273.

Study of the target cell of the dengue virus-induced suppressor signal.

M I Shukla, U C Chaturvedi
PMCID: PMC2040952  PMID: 6201186

Abstract

Dengue type 2 virus (DV) induces two generations of T suppressor cells (Ts1 and Ts2) in murine spleen. The Ts2 cells produce a soluble factor ( SF2 ) which suppresses DV-specific IgM antibody plaque-forming cells (PFC). In this study the target cell of SF2 was examined. The results show that SF2 requires a third generation of T cells (T3) in order to mediate suppression. The surface phenotype of this T3 cell is Ly 1+ and the suppression mediated is antigen specific.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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