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. 1994 Feb;176(3):840–847. doi: 10.1128/jb.176.3.840-847.1994

The mannitol repressor (MtlR) of Escherichia coli.

R M Figge 1, T M Ramseier 1, M H Saier Jr 1
PMCID: PMC205122  PMID: 8300537

Abstract

The mannitol operon of Escherichia coli, encoding the mannitol-specific enzyme II of the phosphotransferase system (Mt1A) and mannitol phosphate dehydrogenase (Mt1D), is here shown to contain a single additional downstream open reading frame which encodes the mannitol repressor (Mt1R). Mt1R contains 195 amino acids and has a calculated molecular weight of 21,990 and a calculated pI of 4.5. It is homologous to the product of an open reading frame (URF2D) upstream of the E. coli gapB gene but represents a novel type of transcriptional regulatory protein.

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Selected References

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