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British Journal of Experimental Pathology logoLink to British Journal of Experimental Pathology
. 1972 Oct;53(5):457–464.

The Effect of Osmolality on the Response of Escherichia coli and Proteus mirabilis to Penicillins

D Greenwood, F O'Grady
PMCID: PMC2072481  PMID: 4563453

Abstract

The response of broth cultures of Escherichia coli and Proteus mirabilis to ampicillin was continuously monitored turbidometrically. The rapid lytic response which follows a few minutes after addition of the antibiotic as well as the later slow lysis of spheroplasts could be manipulated by altering the osmolality of the medium. A higher osmolality was found to be necessary to protect Esch. coli than Pr. mirabilis and this explains the differential response of the 2 organisms that we have previously described.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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