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. 1992 Dec;174(23):7854–7858. doi: 10.1128/jb.174.23.7854-7858.1992

TerF, the sixth identified replication arrest site in Escherichia coli, is located within the rcsC gene.

B Sharma 1, T M Hill 1
PMCID: PMC207506  PMID: 1447156

Abstract

We report the existence of a sixth replication arrest site, TerF, that is located within the coding sequences of the rcsC gene, a negative regulator of capsule biosynthesis. The TerF site is oriented to allow transcription of the rcsC gene but prevent DNA replication in the terminus-to-origin direction. Our results demonstrate that the TerF site is functional in both chromosomal and plasmid environments and that the stability of the Tus-TerF protein-DNA complex more closely resembles the plasmid R6K Ter sites than the chromosomal TerB site.

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Selected References

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