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. 1988 Jun;170(6):2860–2865. doi: 10.1128/jb.170.6.2860-2865.1988

Evidence for endonucleolytic cleavages in decay of lacZ and lacI mRNAs.

M N Subbarao 1, D Kennell 1
PMCID: PMC211215  PMID: 2836375

Abstract

S1 nuclease mapping revealed lacZ mRNA molecules whose 5' and 3' ends were internal to the transcription start and consistent with cleavages at pyrimidine-adenosine bonds 20 to 50 nucleotides apart. With the net 5'-to-3' direction known, lacZ mRNA is probably degraded by sequential cleavages of naked mRNA at vulnerable sites exposed by transit of the last translating ribosome.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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