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. 1986 Nov;168(2):1010–1013. doi: 10.1128/jb.168.2.1010-1013.1986

Partition functions of unit-copy plasmids can stabilize the maintenance of plasmid pBR322 at low copy number.

S Austin, S Friedman, D Ludtke
PMCID: PMC213585  PMID: 3536844

Abstract

The maintenance of plasmid pBR322 is highly unstable in a polA12 strain of Escherichia coli at 29 degrees C due to severely reduced copy number. Under these conditions, introduction of the par (partition) locus of plasmid P1 or the par (sop) region of F into pBR322 stabilizes it. A region with similar activity was detected in the P7 plasmid. The activity of the P1 par locus was dependent on the P1 parA gene product and was sensitive to par-specified incompatibility.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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