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. 1982 Mar;149(3):1082–1088. doi: 10.1128/jb.149.3.1082-1088.1982

Evidence that the two Escherichia coli groE morphogenetic gene products interact in vivo.

K Tilly, C Georgopoulos
PMCID: PMC216498  PMID: 6460751

Abstract

The Escherichia coli groEL and groES gene products are essential for both phage morphogenesis and bacterial growth. Although the gene products have been identified, their exact roles in these processes are not known. We have isolated mutations in the groEL gene that suppress defects in the groES gene. These intergenic suppressors were shown to map in the groEL gene by a variety of genetic and biochemical analyses. These results suggest that the two morphogenetic gene products interact in vivo and help to explain why mutations in either gene exhibit the same phenotype with respect to lambda head assembly and bacterial growth.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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