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. 1969 Nov;100(2):1037–1043. doi: 10.1128/jb.100.2.1037-1043.1969

Characteristics of Virulent, Attenuated, and Avirulent Mycoplasma pneumoniae Strains

Richard P Lipman 1, Wallace A Clyde Jr 1, Floyd W Denny 1
PMCID: PMC250191  PMID: 5359607

Abstract

Homologous pairs of virulent and attenuated or avirulent Mycoplasma pneumoniae strains were derived and compared in an effort to elucidate the mechanisms of virulence. These related strains were found to vary in growth, glycolysis, protein electrophoretic patterns, peroxide formation, morphology, and cytadsorption. Variations in the last two characteristics closely correlated with avirulence. This enables understanding of one stage in the pathogenic sequence and provides a convenient marker for avirulence. The derivation of infectious avirulent strains may make possible their use as live vaccines against M. pneumoniae disease.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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