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. 1972 Dec;112(3):1177–1183. doi: 10.1128/jb.112.3.1177-1183.1972

Effect of Elevated Temperatures on Protein Synthesis in Escherichia coli

David Patterson a,1, David Gillespie b,2
PMCID: PMC251546  PMID: 4565533

Abstract

Upon a temperature shift from 30 C to 42 to 44 C, Escherichia coli experiences a transient slowdown in rate of optical density increase, uridine incorporation, and amino acid incorporation. The data show that the primary target for thermal inactivation is a molecule(s) required for the initiation of protein synthesis. The effect on ribonucleic acid synthesis is a secondary effect.

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Selected References

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