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. 1984 May;50(2):425–431. doi: 10.1128/jvi.50.2.425-431.1984

Characteristics and functions of Sendai virus-specific T-cell clones.

H C Ertl, R W Finberg
PMCID: PMC255636  PMID: 6323742

Abstract

Several murine Sendai virus-specific T-cell clones were characterized in vitro and in vivo. All T-cell clones were phenotypically Thy-1.2+, and most clones were Lyt-1+,2-; one T-cell clone was Lyt-1-,2-. Some of the clones proliferated in response to antigen presented on I region-compatible stimulator cells. Proliferation could be inhibited by monoclonal antibodies directed against class II antigens. Clones which proliferated in response to antigen secreted lymphokines which could be identified as Interleukin 2 and Interleukin 3. All of the clones tested in vivo induced a delayed-type hypersensitivity response in syngeneic mice challenged with antigens. Depending on the experimental conditions chosen, Interleukin 2-producing clones as well as non-Interleukin 2-producing clones mediated help for stimulation of cytolytic T lymphocytes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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