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. 1991 Feb;59(2):716–717. doi: 10.1128/iai.59.2.716-717.1991

Lipopolysaccharide from Klebsiella pneumoniae inhibits Na+ absorption in canine tracheal epithelium.

J Tamaoki 1, N Sakai 1, K Isono 1, T Kanemura 1, K Takeyama 1, T Takizawa 1
PMCID: PMC257818  PMID: 1987086

Abstract

The effect of lipopolysaccharide (LPS) from Klebsiella pneumoniae on the bioelectric properties of canine cultured tracheal epithelium was examined. LPS decreased short-circuit current (Isc), and its effects on Isc were reduced when Isc was inhibited by amiloride and indomethacin. We speculate that LPS may selectively inhibit Na+ absorption through the inhibition of prostaglandin synthesis by airway epithelium.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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