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Proceedings of the National Academy of Sciences of the United States of America logoLink to Proceedings of the National Academy of Sciences of the United States of America
. 1988 Jan;85(2):449–452. doi: 10.1073/pnas.85.2.449

Binding capacity: cooperativity and buffering in biopolymers.

E Di Cera 1, S J Gill 1, J Wyman 1
PMCID: PMC279567  PMID: 3422436

Abstract

The group of linkage potentials resulting from the energy of a physicochemical system expressed per mol of a reference component, say a polyfunctional macromolecule, leads to the concept of binding capacity. This concept applies equally to both chemical and physical ligands and opens the way to consideration of higher-order linkage relationships. It provides a means of exploring the consequences of thermodynamic stability on generalized binding phenomena in biopolymers.

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Selected References

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