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. 1969 Sep;64(1):267–274. doi: 10.1073/pnas.64.1.267

A PROPOSED COMMON ALLOSTERIC MECHANISM FOR ACTIVE TRANSPORT, MUSCLE CONTRACTION, AND RIBOSOMAL TRANSLOCATION*

Terrell L Hill 1
PMCID: PMC286157  PMID: 5263010

Abstract

It is suggested that active transport, muscle contraction, and ribosomal translocation may all make use of a common allosteric mechanism in which ATP or GTP serves as both the effector and substrate and in which a conformational change in a protein (enzyme) moves or exerts a force on a second ligand. The enzymatic splitting of ATP or GTP provides the driving force for the process and allows repetition of the steady-state cycle.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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