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. 1982 Aug;37(2):513–518. doi: 10.1128/iai.37.2.513-518.1982

Growth inhibition of oral streptococci in saliva by anionic proteins from two caries-free individuals.

R A Cowman, S S Baron, R J Fitzgerald, J L Danziger, J A Quintana
PMCID: PMC347564  PMID: 7118248

Abstract

Mixed saliva from two caries-free individuals possessed antimicrobial activity toward Streptococcus mutans and S. sanguis. This inhibitory activity was attributed to the presence of a group of four anionic proteins each of which strongly inhibited the growth of the oral streptococci in a saliva protein-based medium but not in a medium containing amino acids as a nitrogen source. These proteins, with isoelectric points of 4.70, 4.90, 4.98, and 5.05, respectively, neither reacted with antisera to immunoglobulin A, G, or M nor appeared to be functionally related to a number of salivary peroxidases, lactoferrin, or lysozyme. On this basis, they may represent a previously unreported group of growth-inhibitory antimicrobial factors occurring in the saliva of some individuals.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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