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. 1980 Oct;77(10):6101–6104. doi: 10.1073/pnas.77.10.6101

Polymorphism of human B-cell alloantigens: evidence for three loci within the HLA system.

M L Markert, P Cresswell
PMCID: PMC350221  PMID: 6160591

Abstract

The B-cell alloantigens of an HLA-DR3-homozygous, MB2-homozygous, MT2-positive lymphoblastoid cell line were studied by two-dimensional gel electrophoresis. Analysis of gel patterns suggested assignment of the HLA-DR3 determinant to the larger (35,000-dalton) subunit (alpha) of the B-cell alloantigen. MB2 was found to be either a determinant on the small (27,000 dalton) subunit (beta) or a crossreactive determinant(s) on the HLA-DR3 alpha subunit and an additional alpha subunit. MT2 was found to be a determinant on Ia antigen-like molecules distinct from those carrying the MB and HLA-DR determinants. The results are consistent with the existence in the major histocompatibility complex of at least three loci encoding B-cell alloantigens.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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