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. 1979 Jul;16(1):19–27. doi: 10.1128/aac.16.1.19

Isolation and Properties of Metronidazole-Resistant Mutants of Bacteroides fragilis

M L Britz 1,†, R G Wilkinson 1
PMCID: PMC352781  PMID: 475371

Abstract

Metronidazole-resistant mutants of Bacteroides fragilis, isolated after mutagenesis, had diminished ability to take up and metabolize the drug. All the metronidazole-resistant strains had depressed levels of pyruvate dehydrogenase compared with parent cultures. Their end products of glucose metabolism also differed from normal B. fragilis products and were consistent with deficiencies in pyruvate dehydrogenase activity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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