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. 1977 Nov;60(5):1174–1182. doi: 10.1172/JCI108870

Glucagon release from rat pancreatic islets. A combined morphological and functional approach.

J L Carpentier, F Malaisse-Lagae, W A Müller
PMCID: PMC372471  PMID: 409734

Abstract

The release of glucagon induced in isolated rat islets by arginine or by calcium deprivation has been subjected to combined functional and morphological quantifications. Arginine-stimulated glucagon release was associated with a significant increase of morphological events linked to exocytosis. By contrast, the paradoxical events linked to exocytosis. By contrast, the paradoxical release of glucagon provoked by calcium deprivation, although accompanied by a significant loss of granule stores, was not associated with an increase of morphologically detectable exocytosis.

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Selected References

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