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. 1979 Mar;76(3):1256–1260. doi: 10.1073/pnas.76.3.1256

Differentiation of a rat mammary cell line in vitro.

R Dulbecco, M Bologna, M Unger
PMCID: PMC383229  PMID: 375233

Abstract

We have studied the development of fusiform (probably related to myoepithelial) cells in Rama 25 cultures [Bennett, D. C. Peachey, L. A., Durbin, H. & Rudland, P. S. (1978) Cell 15, 283--298]; we show that they are generated from special differentiated structures (projections) that contain a rapidly differentiating cell type (F-precursor cells). Clonal sublines isolated from projections develop in several directions under both environmental and genetic control. Some types of differentiation are reversible; others are irreversible. The various cell occurring in vitro may correspond to specific cell types in vivo.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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