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. 1995 Apr 18;14(8):1812–1818. doi: 10.1002/j.1460-2075.1995.tb07169.x

Sequence-dependent bending propensity of DNA as revealed by DNase I: parameters for trinucleotides.

I Brukner 1, R Sánchez 1, D Suck 1, S Pongor 1
PMCID: PMC398274  PMID: 7737131

Abstract

Structural parameters characterizing the bending propensity of trinucleotides were deduced from DNase I digestion data using simple probabilistic models. In contrast to dinucleotide-based models of DNA bending and/or bendability, the trinucleotide parameters are in good agreement with X-ray crystallographic data on bent DNA. This improvement may be due to the fact that the trinucleotide model incorporates more sequence context information than do dinucleotide-based descriptions.

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Selected References

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