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. 1978 Feb;75(2):946–950. doi: 10.1073/pnas.75.2.946

Assignment of genes to regions of mouse chromosomes.

E M Eicher, L L Washburn
PMCID: PMC411375  PMID: 273256

Abstract

A genetic mapping procedure, called the duplication-deficiency method, is described. This method permits the genetic location of a translocation to be determined within a linkage group without the use of recombination. By utilizing the duplication-deficiency method to define the genetic breakpoints for a series of translocations involving a given chromosome and integrating this information with their cytological breakpoints, obtained by Giemsa banding, a genetic map of the chromosomes is constructed whereby groups of loci are assigned to banded regions. Duplication-deficiency mapping and Giemsa banding analysis of the T(X;7)1Ct and T(7;19)145H translocations together with information from the c25H deletion have permitted mouse chromosome 7 to be divided into six and chromosome 19 into two definable genetic regions.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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