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. 1977 Jul;17(1):117–120. doi: 10.1128/iai.17.1.117-120.1977

Chemiluminescence by human alveolar macrophages: stimulation with heat-killed bacteria or phorobol myristate acetate.

G D Beall, J E Repine, J R Hoidal, F L Rasp
PMCID: PMC421090  PMID: 885610

Abstract

Chemiluminescence of human alveolar macrophages (AM) was evaluated in vitro. Unstimulated AM generated chemiluminescence that remained constant during incubation. Addition of heat-killed Staphylococcus aureus 502A (HKB) or a chemical agent, phorbol myristate acetate, produced high rates of chemiluminescence that were significantly (P less than 0.05) increased over unstimulated AM. Phorbol myristate acetate-and HKB-stimulated increases in AM chemiluminescence were completely blocked by the enzyme superoxide dismutase. In comparison with unstimulated polymorphonuclear leukocytes, unstimulated AM had significantly (P less than 0.005) greater levels of chemiluminescence. However, after stimulation by phorbol myristate acetate or HKB, AM showed less chemiluminescence than similarly treated polymorphonuclear leukocytes.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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