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. 1978 Oct;22(1):69–71. doi: 10.1128/iai.22.1.69-71.1978

Experimental Q fever infection in congenitally athymic nude mice.

R A Kishimoto, H Rozmiarek, E W Larson
PMCID: PMC422117  PMID: 730352

Abstract

Congenitally athymic nude (nu/nu) mice and their phenotypically normal (nu/+) euthymic littermates were exposed to Coxiella burnetii administered as small-particle aerosols. After challenge, both strains of mice became infected, as characterized by rickettsemia, viable rickettsiae in the spleen, and serological conversion. The major difference noted was that euthymic animals had cleared rickettsiae from peripheral circulation and the spleen within 14 days. In contrast, rickettsiae were detected and isolated from spleen and blood of athymic mice through 60 days.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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